The Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) recommends the use of all available COVID-19 vaccines for use as boosters in certain populations.

The recommendation follows the Food and Drug Administration’s (FDA) amendment to the Emergency Use Authorizations for the Moderna COVID-19 vaccine and Janssen COVID-19 vaccine authorizing use of booster doses. On Thursday, CDC Director Rochelle P. Walensky, MD, MPH endorsed the ACIP’s recommendations.

“The evidence shows that all three COVID-19 vaccines authorized in the United States are safe, as demonstrated by the over 400 million vaccine doses already given,” said Walensky in a press statement.

The CDC recommendations also allow for the use of a heterologous (or “mix and match”) booster dose for all currently authorized and approved COVID-19 vaccines.

In individuals who received the Pfizer-BioNTech or Moderna COVID-19 vaccines, a booster dose may be administered at least 6 months after completion of the primary series to individuals 65 years of age and older, as well as to people 18 to 64 years old at high risk of severe COVID-19 or to those with frequent institutional or occupational exposure to SARS-CoV-2.

For those who received the Janssen COVID-19 vaccine, a booster dose may be administered at least 2 months after completion of the single-dose primary regimen in individuals 18 years of age and older.


CDC expands eligibility for COVID-19 booster shots. News release. October 21, 2021.