A new study shows that people who have aspirin resistance may be more likely to have more severe and larger strokes than those who are still responsive to aspirin. Findings from the study will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, DC.

The study evaluated 310 patients who had an ischemic stroke, which involved blood clots, and had been taking aspirin for at least seven days prior to the first stroke symptoms. Aspirin resistance was seen in 27.7% of patients (n=86), and the group’s median stroke severity score was 4 (range 3–11). For patients who were responsive to aspirin, the average stroke severity score was 3 (range 1–6).

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Researchers also found that the stroke impacted larger areas of the brain in patients who were aspirin resistant when measured by MRI diffusion weighted imaging. The infarct size was 2.8cc in those who were aspirin resistant vs. 1.6cc in those who were responsive to aspirin.

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