(HealthDay News) – For some individuals, use of cranberry-containing products appear to protect against urinary tract infections (UTIs).

Chih-Hung Wang, MD, of the National Taiwan University Hospital in Taipei, and colleagues conducted a systematic review and meta-analysis of 13 randomized controlled trials involving 1,616 subjects. The trials compared prevention of UTIs in users of cranberry-containing products versus placebo or non-placebo controls.

The researchers found that, after exclusion of one outlier study, the random-effects pooled risk ratio (RR) for cranberry users was 0.62 compared with nonusers, with moderate heterogeneity (I² = 43%). Cranberry-containing products were found to be more effective in women with recurrent UTIs (RR, 0.53); in women (RR, 0.49) and children (RR, 0.33); in cranberry juice drinkers compared with those who used cranberry capsules or tablets (RR, 0.47); and in people who used cranberry-containing products more than twice per day (RR, 0.58).

“In conclusion, the results of the present meta-analysis support that consumption of cranberry-containing products may protect against UTIs in certain populations,” the authors write. “However, because of the substantial heterogeneity across trials, this conclusion should be interpreted with great caution.”

Continue Reading

Full Text