The FDA has approved Ampyra (dalfampridine extended-release tablets, from Elan and Acorda Therapeutics) to improve walking in adults with multiple sclerosis (MS). Ampyra exerts its effects by closing the exposed potassium channels on demyelinated axons which cause nerve impulse “short circuits”, subsequently improving nerve impulse conduction. In clinical trials, patients treated with Ampyra had faster walking speeds than those treated with placebo.

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