Silvergate announced that the Food and Drug Administration (FDA) has approved Qbrelis (lisinopril) Oral Solution for the treatment of hypertension in patients aged ≥6 years, as adjunct therapy for heart failure, and for the treatment of acute myocardial infarction in adults.

Qbrelis is the first oral solution formulation of lisinopril. The ready-to-use oral solution allows weight-based dosing for children ≥6 years who have had to rely on modified adult doses. Patients with swallowing difficulties may also benefit from Qbrelis Oral Solution. 

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Lisinopril is an ACE inhibitor that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. The effects of lisinopril in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin-aldosterone system. Inhibition of ACE results in decreased plasma angiotensin II which leads to decreased vasopressor activity and to decreased aldosterone secretion. 

Qbrelis Oral Solution will be available as a 1mg/mL strength solution with a sweet taste in 150mL bottles. 

For more information call (855) 379-0382 or visit