Roche Laboratories has announced that it has discontinued the manufacture and distribution of Accutane (isotretinoin capsules). The withdrawal of Accutane from the U.S. market is due to business reasons, and is not related to reasons of safety or efficacy. Isotretinoin will continue to be available generically.

Accutane was indicated for the treatment of severe recalcitrant nodular acne unresponsive to conventional therapy (eg, systemic antibiotics).

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