IDWEEK 2017 – Vaccines

Researchers assessed the risk of febrile seizures following inactivated influenza vaccine and pneumococcal conjugate vaccine-13 during 2013-14 and 2014-15 flu seasons.

Two sequential administration groups were compared by demonstrating the antibody response curve and the reverse cumulative distribution curve analyses by serotype.

For adults aged ≥65 years, seasonal flu epidemics pose significant disease burden annually and not many vaccines are specifically formulated for this patient population.

The researchers conducted the study because protection against herpes zoster has been “shown to wane with time” and effect sizes “can be imprecise”.

The researchers reviewed the VAERS forms and available medical records of serious reports (death, life-threatening illness, hospitalization, prolongation of hospitalization and permanent disability), and reports of Kawasaki disease and anaphylaxis.

The number of acute exacerbations, hospitalizations, ICU admissions, invasive mechanical ventilation, and mortality were analyzed in the study for 146 patients with spirometry-confirmed COPD.

A retrospective cross-sectional study among young, healthy military workers examined associations between 25(OH)D levels and post-vaccination antibody titers and healthcare encounters for respiratory infections.