IDWEEK 2016

Retrospective chart reviews were conducted for Black, genotype 1 (GT1), HIV/HCV co-infected patients treated with ledipasvir/sofosbuvir (LDV/SOF) at 3 hospitals.

The authors gathered clinical and demographic data from the University of Kentucky Center for Clinical and Translational Science Enterprise Data Trust, for adults who received TZP+VAN or CFP+VAN for ≥48 hours in the ICU.

With international travel, “any outbreak, anywhere in the world can be a threat, everywhere.” That’s the reality of an increasingly connected world, said Malik Peiris, PhD, of the School of Public Health at the HKU-Pasteur Research Center, The University of Hong Kong, Pokfulam, Hong Kong, at IDWeek 2016.

Long-term use of proton pump inhibitors (PPIs) might increase microbial translocation and innate immune activation but not enterocyte turnover or T-cell activation among people infected with HIV-1, according to research findings reported at IDWeek 2016.

GSK Vaccines’ investigational meningococcal vaccine against serogroups A, B, C, W and Y (MenABCWY) is broadly effective among adolescents, according to the company’s phase 2b, observer-blind, multicenter study, reported at IDWeek 2016.

HIV and hepatitis B virus (HBV) drugs had no impact on antiviral activity of grazoprevir or elbasvir, and neither agent affected HIV and HBV replication, a study presented at IDWeek has shown.

Together, depression and HIV infection are “strongly associated” with all-cause mortality in U.S. veterans, results from one of the largest analyses to date to examine this association reported at IDWeek 2016.

Extended-interval aminoglycoside dosing “appears of be safe in pediatric patients,” a retrospective study presented at IDWeek has found.

In children with cancer, concurrent vancomycin and piperacillin-tazobactam administration may increase risk of acute kidney injury, a retrospective study presented at IDWeek has shown.

Vitamin D deficiency is prevalent among treatment-naïve HIV-infected patients, researchers reported at IDWeek 2016.