American Pain Society 2012

American Pain Society 2012

IV Lidocaine Shows Promise in Quality of Life Improvement During Postoperative Recovery

A trend towards less pain, functional interference and drowsiness, and improved patient satisfaction exists in patients who received continuous intravenous (IV) lidocaine treatment perioperatively, according to preliminary data from an ongoing, prospective, matched cohort, quality improvement study presented at the American Pain Society’s 31st Annual Scientific Meeting.

Diclofenac Sodium 1% Gel Minimizes Drug-Drug Interaction-Related Adverse Events

Minimal systemic distribution of topical diclofenac sodium gel resulted in a lower incidence of major or moderate drug-drug interactions associated with oral diclofenac and reduced the risk of drug interaction-related adverse events. Study results were reported by Matthew Wieman, MD, from Endo Pharmaceuticals, John H. Peniston, DO, from Novartis Consumer Health, and colleagues at the American Pain Society’s 31st Annual Scientific Meeting.

Vitamin D Deficiency Associated With Increased Osteoarthritis Symptoms and Reduced Pain Threshold

Study investigators presented data from the UPLOAD (Understanding Pain & Limitations in OsteoArthritic Disease) study at the American Pain Society’s 31st Annual Scientific Meeting demonstrating that hydroxyvitamin D levels <25ng/mL were associated with an increase in osteoarthritis (OA) symptoms and a decreased threshold for pressure pain.

Secondary Opioid Use in Postherpetic Neuralgia Suggests Suboptimal Gabapentin, Pregabalin Titration

The percentage of patients in community-practice settings who newly initiate opioid therapy while taking gabapentin and pregabalin for postherpetic neuralgia suggest these agents should be titrated to higher and potentially more effective dosages, a study presented at the American Pain Society’s 31st Annual Scientific Meeting has found.

OROS Hydromorphone ER: No Sustained Efficacy for Osteoarthritis Pain vs. Placebo

A randomized, placebo-controlled, double-blind study evaluating OROS hydromorphone ER for reducing moderate-to-severe osteoarthritis (OA) pain showed that though the treatment is effective in treating chronic OA, it failed to demonstrate sustained efficacy vs. placebo + rescue medication, “perhaps due to higher use of rescue medication in the latter group,” investigators concluded during a presentation at the American Pain Society’s 31st Annual Scientific Meeting.