American Pain Society 2012

Gender Differences in Pain Management: The Effect of Sexual Dimorphism

At the American Pain Society’s 31st Annual Scientific Meeting, Jon Levine, MD, PhD discussed recent data showing that kappa-opioids, generally observed to be less effective in providing pain relief than mu-receptor opioids, were not only equally effective in producing pain relief in a female patient population, but were also associated with a reduced incidence of adverse effects and greater overall patient satisfaction.

IV Prochlorperazine Effective for Pediatric Primary Intractable Migraine

Intravenous (IV) prochlorperazine is more effective for the acute treatment of refractory migraine in pediatric patients than IV metoclopramide or valproate sodium. Shannon Cherney, MSN, CNP, from the Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, and colleagues sought to evaluate the efficacy of various IV pharmacotherapy options for primary intractable headache in children. The results were presented today at the American Pain Society’s 31st Annual Scientific Meeting.

Flexible Multiday Dosing of Etoricoxib Reduces Recall Pain and Rescue Medication Use

A multiday, flexible dosing regimen of etoricoxib demonstrated greater improvements in worst recall pain, as well as reduced usage of study and rescue medication, compared with other standard therapies. Study investigators reported at the American Pain Society’s 31st Annual Scientific Meeting that the efficacy of etoricoxib was evaluated in a third-molar dental extraction study.