APS 2012: Neuropathic Pain

Secondary Opioid Use in Postherpetic Neuralgia Suggests Suboptimal Gabapentin, Pregabalin Titration

The percentage of patients in community-practice settings who newly initiate opioid therapy while taking gabapentin and pregabalin for postherpetic neuralgia suggest these agents should be titrated to higher and potentially more effective dosages, a study presented at the American Pain Society’s 31st Annual Scientific Meeting has found.

Pregabalin Rapidly Improves Sleep in Painful Diabetic Peripheral Neuropathy, Postherpetic Neuralgia

Patients with diabetic peripheral neuropathy (DPN) or postherpetic neuralgia (PHN) treated with pregabalin have rapid, significant, and sustained improvement in sleep, according to a posthoc analysis of 16 placebo-controlled trials of pregabalin in 4,527 patients reported during the American Pain Society’s 31st Annual Scientific Meeting.