APS 2012: Chronic Pain

OROS Hydromorphone ER: No Sustained Efficacy for Osteoarthritis Pain vs. Placebo

A randomized, placebo-controlled, double-blind study evaluating OROS hydromorphone ER for reducing moderate-to-severe osteoarthritis (OA) pain showed that though the treatment is effective in treating chronic OA, it failed to demonstrate sustained efficacy vs. placebo + rescue medication, “perhaps due to higher use of rescue medication in the latter group,” investigators concluded during a presentation at the American Pain Society’s 31st Annual Scientific Meeting.