Families often preferred to remain on treatment despite the risk of vision loss.
AES 2017
The results suggest that a change in the way perampanel is initiated may be warranted.
Researchers examined seizure outcome at 6 months following slow initiation of KD in 40 children. The diet was initiated at a very low ratio (0.6 to 1:1) and was increased gradually depending on the tolerability and desired seizure control.
Researchers assessed the relationship between maternal antibiotic use and neonatal seizures in infants (>32 weeks gestation).
ESL is not currently FDA-approved for use in pediatric patients.
When compared to lamotrigine, levetiracetam was found to increase seizure-freedom, however, it was also associated with an increased risk of side effects.
Odds of achieving a clinically meaningful (≥50%) or substantial (≥75%) reduction in convulsive seizure frequency were 29 and 50 times higher, respectively, among patients treated with ZX008 than in patients treated with placebo.
For all POS and for most POS subtypes, pregabalin resulted in a numerically greater percentage of subjects who exhibited categorical decreases in seizure frequency vs placebo.
Trends of suicide related behavior were compared before and after initiation of AED therapy among AED users with and without epilepsy to individuals without AED use.
At baseline, the patients included in the study were an average (SD) age of 12.4 (9.0) years old with an average (SD) 86.6 (161.5) drop seizures/week.
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