AAN 2016 Neurodegenerative Disease

In elderly patients with cognitive dysfunction undergoing surgery for hip fracture, perioperative application of the rivastigmine patch reduced incidence postoperative delirium.

IncobotulinumtoxinA injections customized by site and dose improved hand and forearm tremor symptoms patients with Parkinson’s disease without increasing hand weakness

Levodopa-carbidopa intestinal gel is safe and effective in Japanese, Taiwanese, and Korean patients with advanced Parkinson’s disease

Parkinson’s disease (PD) “off”-period symptoms control is better following administration of an inhaled levodopa powder formulation (CVT-301) than placebo.

A study of 137 patients found edaravone use lead to less functional loss than placebo, contrasting with results from a previous Phase 3 study which found no efficacy of the treatment over placebo.

For patients with moderate to severe Alzheimer’s disease, adding memantine to cholinesterase inhibitor treatment can improve daily life task functions, results of post-hoc pooled factor analysis presented at the 68th AAN Annual Meeting have shown.

Dextromethorphan/quinidine (DM/Q) is effective in treating pseudobulbar affect (PBA) – involuntary laughing and crying – in treating dementia, stroke and TBI patients as well as amyotrophic lateral sclerosis and multiple sclerosis (MS).

Patients with advanced Parkinson’s disease had resting tremors improved with levodopa-carbidopa intestinal gel, a study presented at the 68th Annual AAN Meeting has found.