All-cause health care costs during the post-index period were 6.5% greater for the vial/syringe cohort in the MarketScan database. In the LifeLink database, all-cause health care costs were 2.7% greater in the vial/syringe cohort than in the pen cohort, but the difference was not statistically significant.

The researchers concluded, “Although insulin pens are associated with greater acquisition costs than vials/syringes, the greater cost of health care associated with vial/syringe use in two independent database analyses demonstrates the cost advantage of pens over vials/syringes.”

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