Arguably, QoL may be an even more relevant outcome in MS patient than more traditional measurements, such as disability or neurological impairment.1 Clinicians should remain cognizant of the “invisible” issues that contribute to impaired QoL, initiate discussions with patients, and make helpful interventions available.

Table 1. Factors that Impact QoL in Patients with MS

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  • Cognitive decline
  • Fatigue
  • Isolation
  • Sexual Dysfunction
  • Family dynamics
  • Relationship issues
  • Inability, or reduced ability, to work
  • Bladder disorders
  • Depression
  • Treatment adherence


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