A Simple Complaint of Vaginal Discharge May Signal a Lot More

Sex hormone use among women declined (19% to 11%), primarily because of a decline in noncontraceptive hormones (comprised largely of menopausal HRT). This is an interesting finding given conjugated estrogens once were the most commonly used prescription drug.
Sex hormone use among women declined (19% to 11%), primarily because of a decline in noncontraceptive hormones (comprised largely of menopausal HRT). This is an interesting finding given conjugated estrogens once were the most commonly used prescription drug.
Mrs. M, a 58-year-old woman comes to your office as a new patient with a primary complaint of vaginal discharge.

Mrs. M, a 58-year-old woman comes to your office as a new patient with a primary complaint of vaginal discharge. 

HISTORY
Mrs. M is well groomed, communicates well, and works in central processing at a neighboring hospital. She was diagnosed with breast cancer three years ago and has been receiving tamoxifen therapy following her lumpectomy. She has been repeatedly treated for a yeast infection by her primary-care provider, but says the symptoms have not improved. She is going through a divorce and has not had sexual intercourse for “almost a year.”

EXAMINATION
Mrs. M’s vital signs on physical examination:  BP 130/70mm Hg; pulse 84bpm. She is 5′ 7” tall and weighs 160lbs. Her last menstrual period was at age 50. 

On physical examination:

            Vulva: Normal, no lesions

            Vagina: Moderate green/yellow discharge, erythematous vaginal epithelium; atrophic changes

            Wet prep: WBCs; no yeast forms noted

            Cervix: Petechiae

            Uterus: Small, AV, non-tender, mobile

            Adnexa: Small ovaries palpable consistent with menopause

DIAGNOSIS AND DISCUSSION
Based on the findings, Mrs. M may have atrophic vaginitis or possible infectious vaginitis. A vaginal culture should be obtained to rule out a sexually transmitted infection and noninfectious organisms (yeast, bacteria). A vaginal moisturizer should be recommended, as Mrs. M is not a candidate for local estrogen therapy if diagnosed with atrophic vaginitis (per breast surgeon/oncologist). Patient education should be provided regarding estrogen loss and vaginal health.