Oral Urinary Tract Infection Treatments
Generic Brand Form Strength Adult Dose Duration
cefadroxil caps 500mg Uncomplicated UTI: 1−2g once daily or in 2 divided doses
Complicated UTI: 2g/day in 2 divided doses
tabs 1g
susp 250mg/5mL, 500mg/5mL
cefixime Suprax chew tabs 100mg, 150mg, 200mg 400mg once daily or 200mg every 12hrs  
susp 200mg/5mL, 500mg/5mL
cefpodoxime granules for susp 50mg/5mL, 100mg/5mL 100mg every 12hrs 7 days
tabs 100mg, 200mg
cefuroxime tabs 250mg, 500mg 250mg twice daily 7−10 days
cephalexin Keflex caps 250mg, 500mg, 750mg 250mg every 6hrs; may give 500mg every 12hrs. Max 4g/day in 2–4 equally divided doses 7−14 days
nitrofurantoin Furadantin susp 25mg/5mL 50−100mg 4 times daily.
Suppressive therapy: 50−100mg once daily at bedtime may suffice
Macrobid caps 100mg 100mg every 12hrs 7 days
caps 25mg, 50mg, 100mg 50−100mg 4 times daily.
Long-term use: 50−100mg once daily at bedtime
7 days
amoxicillin caps 250mg, 500mg 500mg every 12hrs or 250mg every 8hrs. Severe infections: 875mg every 12hrs or 500mg every 8hrs.
tabs 500mg, 875mg
susp 125mg/5mL, 250mg/5mL
amoxicillin/ clavulanic acid chewable 200mg/28.5mg, 400mg/57mg 500mg every 12hrs or 250mg every 8hrs. Severe infections: 875mg every 12hrs or 500mg every 8hrs.
tabs 250mg/125mg, 500mg/125mg, 875mg/125mg
Augmentin tabs 875mg/125mg
susp 125mg/31.25mg/ 5mL, 250mg/ 62.5mg/5mL
ciprofloxacin Cipro tabs 250mg, 500mg Acute uncomplicated cystitis due to E. coli, S. saprophyticus in females: 250mg every 12hrs. 3 days
susp 250mg/5mL, 500mg/5mL
Other UTI: 250−500mg every 12hrs 7−14 days
Cipro XR ext‑rel tabs 500mg, 1g Uncomplicated UTI: 500mg once daily 3 days
Complicated UTI, acute uncomplicated pyelonephritis: 1000mg once daily 7−14 days
levofloxacin soln 25mg/mL Uncomplicated UTI: 250mg once daily. Complicated UTI, acute pyelonephritis: 250mg once daily or 750mg once daily 3 days
tabs 250mg, 500mg, 750mg 250mg dose: 10 days
750mg dose: 5 days
ofloxacin tabs 200mg, 300mg, 400mg Uncomplicated cystitis: 200mg every 12hrs 3 days (E. coli or K. pneu
); 7 days (other)
Complicated: 200mg every 12hrs 10 days
oxazole/ trimethoprim
susp 200mg/ 40mg/ 5mL 20mL every 12hrs 10−14 days
Bactrim tabs 400mg/ 80mg 2 tabs every 12hrs
Bactrim DS tabs 800mg/ 160mg 1 tab every 12hrs
Septra DS
fosfomycin Monurol granules for soln 3g Uncomplicated UTI: Females: Mix 1 sachet with 3−4oz of water (do not use hot water); drink immediately. Max 1 dose/episode. 1 dose
trimethoprim tabs 100mg, 200mg Uncomplicated UTI: 100mg twice daily, or 200mg once daily 10 days
Not an inclusive list of medications. Please see drug monographs at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 2/2021)