Do Not Crush or Chew

DO NOT CRUSH OR CHEW

Allergic Disorders

 

Orally-Disintegrating Tablets: Alavert ODT, Claritin Reditabs, Desloratadine ODT

 

Cardiovascular DISEASE

Sustained-Release: Adalat CC, Altoprev, Calan SR, Cardizem CD1, Cardizem LA, Coreg CR1, Dilatrate SR, felodipine, Inderal LA, Innopran XL, Kapvay, Lescol XL, Niaspan, Norpace CR, pentoxifylline, Procardia XL, Ranexa, Rythmol SR, Sular, Tiazac1, Toprol XL6, Verelan1, Verelan PM1

 

Sublingual: Isosorbide dinitrate, Nitrostat

 

Misc: Letairis, Lovaza, Pradaxa8

 

Dermatological Disorders

Sustained-Release: Diamox, Doryx1, Oracea, Solodyn

 

Misc: Minocin2, Propecia4

 

Endocrine Disorders

Sustained-Release: Fortamet, Glucophage XR, Glucotrol XL, Glumetza, Janumet XR, Kombiglyze XR, Rayos, Zemplar

 

Buccal: Striant

 

Misc: Sensipar7

 

GASTROHEPATIC DISORDERS

Sustained-Release: Apriso, Colestid, Dexilant, Lialda, Pentasa, Uceris, Zegerid

 

Enteric Coated: AcipHex, Asacol, Azulfidine EN‑tabs, Creon1, Dulcolax5, Entocort EC, Fleet, Nexium1, Prevacid1, Prilosec1, Protonix

 

Orally-Disintegrating Tablets: Prevacid Solutab, Zofran ODT

 

Misc: Amitiza5, Colace10, Marinol5, Pepto-Bismol Caplet7

 

IMMUNE DISORDERS & ONCOLOGY

Sustained-Release: Myfortic

 

Misc: Afinitor, Cellcept4, Erivedge 2,4, Jakafi3, Rapamune8, Revlimid4, Sprycel4,9, Tasigna8, Temodar2, Votrient8, Zolinza2, Zortress

 

INFECTIOUS DISEASES

Sustained-Release: Augmentin XR, Biaxin XL, Cipro XR, Doryx, Ery-Tab, Flagyl ER, Noxafil

 

Enteric-Coated: Eryc, Videx EC

 

Misc: Aptivus5, Biltricide10, Ceftin10, Clotrimazole Troches, Kaletra9, Minocin2, Valcyte4,9

 

Musculoskeletal Disorders

Sustained-Release: Amrix, Atelvia8, Indomethacin ER, Mestinon Timespan, Naprelan, Tylenol Arthritis, Vimovo

Enteric-Coated: Arthrotec, Azulfidine EN‑tabs, Bayer Arthritis, EC‑Naprosyn, Ecotrin

 

Misc: Actonel2, Boniva2, Evista4,9,10,
Feldene2, Fosamax2, Fosamax+ D2

 

NEUROLOGIC & PSYCHIATRIC DISORDERS

Sustained-Release: Adderall XR1, Ambien CR, Ampyra, Aplenzin, Carbatrol1, Concerta, Cymbalta, Depakene, Depakote, Depakote ER, Depakote Sprinkles, Effexor XR1, Equetro1, Focalin XR1, Horizant, Intuniv, Invega, Keppra XR9,  Lithobid, Metadate CD1, Mirapex ER, Namenda XR, Paxil CR, Phenytek, Pristiq, Razadyne ER, Requip XL, Ritalin LA1, Seroquel XR, Sinemet CR6,
Tecfidera, Tegretol XR Topamax1, Wellbutrin SR/XL, Xanax XR

 

Orally-Disintegrating Tablets: Aricept ODT, Lamictal ODT, Remeron Solutab, Risperdal M‑Tabs, Zelapar, Zyprexa Zydis

 

Sublingual: Zolpidem SL

 

Misc: Strattera11, Treximet8, Zonegran7

Nutrition

Sustained-Release: Diethylpropion SR, Ferro-Sequels, Klor‑Con, Klor‑Con M6, Mag-Tab SR, Slow‑Fe, Slow Fe+ Folic Acid

 

Enteric Coated: Feosol

 

Misc: Drisdol5, K‑Lyte3

 

PAIN MANAGEMENT

Sustained-Release: Actiq (lozenge), Gralise, Kadian1, MS Contin, Nucynta ER7,8 Oxycontin, Topamax1, Tramadol ER, Zohydro ER

 

Orally-Disintegrating Tablets: Maxalt‑MLT, Zomig ZMT

 

Buccal: Fentora

 

Poisoning & Drug Dependence

Sustained-Release: Zyban

 

Enteric-Coated: Acamprosate

 

Sublingual: Suboxone

 

Misc: Exjade3

 

Respiratory DISORDERS

Sustained-Release: Alavert D‑12,
Allegra‑D, Clarinex‑D, Claritin‑D, Mucinex, Sudafed12/24HR, Theo‑24, VoSpire ER, Zyflo CR, Zyrtec‑D

 

Misc: Tessalon2,5

 

UROLOGICAL DISORDERS

Sustained-Release: Cardura XL, Detrol LA, Ditropan XL, Enablex, Flomax, Myrbetriq, Sanctura‑XR, Toviaz, Uroxatral

 

Enteric-Coated: Urocit‑K

 

Misc: Avodart7, Jalyn, Proscar4, Renagel8, Vesicare9


Allergic Disorders

 

Orally-Disintegrating Tablets: Alavert ODT, Claritin Reditabs, Desloratadine ODT

 

Cardiovascular DISEASE

Sustained-Release: Adalat CC, Altoprev, Calan SR, Cardizem CD1, Cardizem LA, Coreg CR1, Dilatrate SR, felodipine, Inderal LA, Innopran XL, Kapvay, Lescol XL, Niaspan, Norpace CR, pentoxifylline, Procardia XL, Ranexa, Rythmol SR, Sular, Tiazac1, Toprol XL6, Verelan1, Verelan PM1

 

Sublingual: Isosorbide dinitrate, Nitrostat

 

Misc: Letairis, Lovaza, Pradaxa8

 

Dermatological Disorders

Sustained-Release: Diamox, Doryx1, Oracea, Solodyn

 

Misc: Minocin2, Propecia4

 

Endocrine Disorders

Sustained-Release: Fortamet, Glucophage XR, Glucotrol XL, Glumetza, Janumet XR, Kombiglyze XR, Rayos, Zemplar

 

Buccal: Striant

 

Misc: Sensipar7

 

GASTROHEPATIC DISORDERS

Sustained-Release: Apriso, Colestid, Dexilant, Lialda, Pentasa, Uceris, Zegerid

 

Enteric Coated: AcipHex, Asacol, Azulfidine EN‑tabs, Creon1, Dulcolax5, Entocort EC, Fleet, Nexium1, Prevacid1, Prilosec1, Protonix

 

Orally-Disintegrating Tablets: Prevacid Solutab, Zofran ODT

 

Misc: Amitiza5, Colace10, Marinol5, Pepto-Bismol Caplet7

 

IMMUNE DISORDERS & ONCOLOGY

Sustained-Release: Myfortic

 

Misc: Afinitor, Cellcept4, Erivedge 2,4, Jakafi3, Rapamune8, Revlimid4, Sprycel4,9, Tasigna8, Temodar2, Votrient8, Zolinza2, Zortress

 

INFECTIOUS DISEASES

Sustained-Release: Augmentin XR, Biaxin XL, Cipro XR, Doryx, Ery-Tab, Flagyl ER, Noxafil

 

Enteric-Coated: Eryc, Videx EC

 

Misc: Aptivus5, Biltricide10, Ceftin10, Clotrimazole Troches, Kaletra9, Minocin2, Valcyte4,9

 

Musculoskeletal Disorders

Sustained-Release: Amrix, Atelvia8, Indomethacin ER, Mestinon Timespan, Naprelan, Tylenol Arthritis, Vimovo

Enteric-Coated: Arthrotec, Azulfidine EN‑tabs, Bayer Arthritis, EC‑Naprosyn, Ecotrin

 

Misc: Actonel2, Boniva2, Evista4,9,10,
Feldene2, Fosamax2, Fosamax+ D2

 

NEUROLOGIC & PSYCHIATRIC DISORDERS

Sustained-Release: Adderall XR1, Ambien CR, Ampyra, Aplenzin, Carbatrol1, Concerta, Cymbalta, Depakene, Depakote, Depakote ER, Depakote Sprinkles, Effexor XR1, Equetro1, Focalin XR1, Horizant, Intuniv, Invega, Keppra XR9,  Lithobid, Metadate CD1, Mirapex ER, Namenda XR, Paxil CR, Phenytek, Pristiq, Razadyne ER, Requip XL, Ritalin LA1, Seroquel XR, Sinemet CR6,
Tecfidera, Tegretol XR Topamax1, Wellbutrin SR/XL, Xanax XR

 

Orally-Disintegrating Tablets: Aricept ODT, Lamictal ODT, Remeron Solutab, Risperdal M‑Tabs, Zelapar, Zyprexa Zydis

 

Sublingual: Zolpidem SL

 

Misc: Strattera11, Treximet8, Zonegran7

Nutrition

Sustained-Release: Diethylpropion SR, Ferro-Sequels, Klor‑Con, Klor‑Con M6, Mag-Tab SR, Slow‑Fe, Slow Fe+ Folic Acid

 

Enteric Coated: Feosol

 

Misc: Drisdol5, K‑Lyte3

 

PAIN MANAGEMENT

Sustained-Release: Actiq (lozenge), Gralise, Kadian1, MS Contin, Nucynta ER7,8 Oxycontin, Topamax1, Tramadol ER, Zohydro ER

 

Orally-Disintegrating Tablets: Maxalt‑MLT, Zomig ZMT

 

Buccal: Fentora

 

Poisoning & Drug Dependence

Sustained-Release: Zyban

 

Enteric-Coated: Acamprosate

 

Sublingual: Suboxone

 

Misc: Exjade3

 

Respiratory DISORDERS

Sustained-Release: Alavert D‑12,
Allegra‑D, Clarinex‑D, Claritin‑D, Mucinex, Sudafed12/24HR, Theo‑24, VoSpire ER, Zyflo CR, Zyrtec‑D

 

Misc: Tessalon2,5

 

UROLOGICAL DISORDERS

Sustained-Release: Cardura XL, Detrol LA, Ditropan XL, Enablex, Flomax, Myrbetriq, Sanctura‑XR, Toviaz, Uroxatral

 

Enteric-Coated: Urocit‑K

 

Misc: Avodart7, Jalyn, Proscar4, Renagel8, Vesicare9

NOTES

1 Contents in caps can be mixed with applesauce to be swallowed immediately and not chewed or crushed. Mixture cannot be stored for later use. See full labeling.

2 Can cause irritation to skin and/or mucous membranes.

3 Must be dissolved in liquid. See literature.

4 May be teratogenic. Pregnant women or women who may become pregnant should avoid contact.

5 Caps are liquid-filled.

6 Scored tabs, can be broken in half but not crushed or chewed.

7 Manufacturer recommends swallowing whole.

8 Pharmacokinetic properties may be compromised if crushed, chewed, or broken apart.

9 Film-coated

10 Taste

11 Ocular irritant

Not an inclusive list of medications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 10/2020)