Bowel Cleansers

BOWEL CLEANSERS
Generic Strength Brand Form Total
Volume1
Usual Dose
PEG FORMULATIONS
High Volume
polyethylene glycol 3350 60g/L Colyte w. Flavor Packs Rx pwd for reconstitution (add 1 flavor pack before reconstitution) 4L oral Adults: After fasting for ≥3hrs, 240mL orally every 10mins or 20–30mL/min by NG tube until fecal discharge is clear. Usual dose 3–4L. Only clear liq until exam.
Children: Not established.

sodium chloride 1.46g/L
potassium chloride 0.745g/L
sodium bicarbonate 1.68g/L
sodium sulfate 5.68g/L
polyethylene glycol 3350 236g/4L GoLytely Rx pwd for reconstitution 4L oral Adults: May consume water or clear liq during and after completion of bowel prep up until 2hrs before procedure. 240mL orally every 10mins or 20–30mL/min by NG tube until rectal effluent is clear or 1 gallon consumed.
Children: Not established.
sodium chloride 5.86g/4L
potassium chloride 2.97g/4L
sodium bicarbonate 6.74g/4L
sodium sulfate 22.74g/4L
polyethylene glycol 3350 420g/4L NuLytely Rx pwd for reconstitution 4L oral Adults: 240mL orally every 10mins or 20–30mL/min by NG tube until rectal effluent is clear or 4L consumed.
Children: <6mos: Not recommended. ≥6mos: 25mL/kg/hr orally or by NG tube until rectal effluent is clear or 4L consumed.
Both: May consume water or clear liq during and after completion of bowel prep up until 2hrs before procedure.
sodium bicarbonate 5.72g/4L
sodium chloride 11.2g/4L
potassium chloride 1.4g/4L
polyethylene glycol 3350 420g/4L TriLyte w. Flavor Packs Rx pwd for reconstitution (add 1 flavor pack before reconstitution) 4L oral Adults: After fasting for 3–4 hrs, 240mL orally every 10mins or 20–30mL/min by NG tube until rectal discharge is clear or 4L consumed. Only clear liq until exam.
Children: <6mos: Not recommended. ≥6mos: No solid food for ≥2hrs, then 25mL/kg/hr orally or by NG tube until rectal discharge is clear or 4L consumed. Only clear liq until exam.
sodium chloride 11.2g/4L
potassium chloride 1.48g/4L
sodium bicarbonate 5.72g/4L
Low Volume
polyethylene glycol 3350 200g/2L MoviPrep Rx pwd for reconstitution4 2L oral Adults: Start the evening before colonoscopy. Split-dose regimen: drink 240mL every 15mins over 1hr until 1L consumed, follow with 480mL of clear liq; in the AM (start ≥3.5hrs before colonoscopy), drink 2nd liter over 1hr, then drink 480mL of clear liq ≥2hrs before colonoscopy. Evening-only regimen: start ≥3.5hrs before bedtime; drink 240mL every 15mins over 1hr until 1L consumed, then drink 2nd liter 1.5hrs later over 1hr; in addition, drink 1L of clear liq.
Children: <18yrs: Not established.
sodium sulfate 15g/2L
sodium chloride 5.38g/2L
potassium chloride 2.03g/2L
ascorbic acid 9.4g/2L
sodium ascorbate 11.8g/2L
polyethylene glycol 3350 140g/32oz Plenvu Rx pwd for reconstitution4 1L oral Adults: Two-day regimen: start the evening before colonoscopy, drink 480mL over 30mins, follow with 480mL of clear liq over next 30mins; in the AM, drink 480mL over 30mins, then drink 480mL of clear liq over next 30mins. Consume additional water or clear liq up to 2hrs before colonoscopy. One-day regimen: start the morning of colonoscopy, drink 480mL over 30mins, follow with 480mL of clear liq over next 30mins. At minimum of 2hrs after first dose, drink 480mL over 30mins, follow with 480mL of clear liq over next 30mins. Consume additional water or clear liq up to 2hrs before colonoscopy.
Children: Not established.
sodium ascorbate 48.11g/32oz
sodium sulfate 9g/32oz
ascorbic acid 7.54g/32oz
sodium chloride 5.2g/32oz
potassium chloride 2.2g/32oz
SODIUM PHOSPHATE FORMULATIONS
monobasic sodium phosphate 19g/197mL Fleet Enema Extra OTC enema2,3 197mL rectal Adults: 1 enema rectally daily; may use up to 7 days. Results usually within 1-5mins; reevaluate if no relief after 7 days.
Children: Use other forms.
dibasic sodium phosphate 7g/197mL
sodium phosphate (as monobasic monohydrate and dibasic anhydrous) 1.5g OsmoPrep Rx tabs Adults: Evening before colonoscopy: 4 tabs with 8oz of clear liq every 15mins for a total of 20 tabs; repeat on day of colonoscopy 3–5hrs before procedure for a total of 12 tabs. Wait 7 days before retreating.
Children: <18yrs: Not recommended.
OTHERS
bisacodyl 10mg/30mL Fleet Bisacodyl Enema OTC enema2 30mL rectal Adults: 1 enema rectally daily. Results usually within 5–20mins; reevaluate if ineffective.
Children: Not recommended.
sodium picosulfate 10mg Clenpiq Rx oral soln (undiluted) 320mL oral Adults and Children: <9yrs: Not established. ≥9yrs: Split-dose regimen: take 1st dose during the evening before colonoscopy (eg, 5–9pm), followed by five or more 8oz cups of clear liq within 5hrs and before bed. Take 2nd dose the next day, start approx. 5hrs before colonoscopy, followed by at least four or more 8oz cups of clear liq up to 2hrs before the procedure.
magnesium oxide 3.5g
anhydrous citric acid 12g
sodium sulfate 1.479g Sutab Rx tabs Adults: Evening before colonoscopy: 12 tabs with 16oz of water over 15–20mins; approx. 1hr after the last tab, drink a second 16oz of water over 30mins; approx. 30mins after the second container of water, drink another 16oz of water over 30mins. Morning of colonoscopy (5–8hrs before procedure and no sooner than 4hrs from starting 1st dose): repeat using next 12 tabs. Complete prep ≥2hrs before colonoscopy.
Children: Not established.
magnesium sulfate 0.225g
potassium chloride 0.188g
sodium sulfate 13.13g/4.5oz; 17.5g/6oz Suprep Rx oral soln for dilution 32oz oral Adults: Evening before colonoscopy: dilute 1 bottle (6oz) to 16oz with water and drink entire amount. Drink 32oz of water over the next hr. Next morning: repeat using the second bottle. Complete prep ≥2hrs before colonoscopy.
Children: <12yrs: Not established. 12–16yrs: Evening before colonoscopy: dilute 1 bottle (4.5oz) to 12oz with water and drink entire amount. Drink 24oz of water over the next hr. Next morning: repeat using the second bottle. Complete prep ≥2hrs before colonoscopy.
potassium sulfate 2.35g/4.5oz; 3.13g/6oz
magnesium sulfate 1.2g/4.5oz; 1.6g/6oz
NOTES

Key: liq = liquid; oz = ounce; pkt = packet; pwd = powder; soln = solution

1 Total volume per regimen; may be undiluted or after reconstitution/dilution

2 Latex free

3 Contains sodium 4.4g/enema

4 Contains phenylalanine

Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 12/2020)