ADHD Treatments
ADHD TREATMENTS
Generic Brand Strength Form Max Dose Administration
amphetamine Adzenys ER CII 1.25mg/mL ext-rel oral susp 6-12yrs: 18.8mg (15mL) daily 
13–17yrs: 12.5mg (10mL) daily

• Give once daily in the AM

• May increase by 3.1mg (2.5mL) or 6.3mg (5mL) at weekly intervals

Adzenys XR-ODT CII 3.1mg, 6.3mg, 9.4mg, 12.5mg, 15.7mg, 18.8mg ext-rel orally disintegrating tabs 6–12yrs: 18.8mg/day 13–17yrs: 12.5mg/day

• Give once daily in the AM

• May increase by 3.1mg or 6.3mg at weekly intervals

Dyanavel XR CII 2.5mg/mL ext-rel oral susp ≥6yrs: max 20mg/day

• Give once daily in the AM

• May increase by 2.5–10mg/day every 4–7 days

amphetamine sulfate Evekeo CII 5mg, 10mg tabs 3–5yrs: initially 2.5mg daily, may increase by 2.5mg/day at weekly intervals ≥6yrs: max 40mg/day

• Avoid late evening doses

• Give first dose upon awakening and additional doses at 4−6hr intervals

Evekeo ODT CII 5mg, 10mg, 15mg, 20mg tabs 6-17yrs: 40mg/day

• Give first dose once or twice daily and additional dose after 4–6hrs

• Titrate in increments of 5mg at weekly intervals

atomoxetine HCl Strattera Rx 10mg, 18mg, 25mg, 40mg, 60mg, 80mg, 100mg caps ≥6yrs: 1.4mg/kg or 100mg/
day (which
ever is less)

• Swallow whole

• Give once daily in the AM or in 2 divided doses (in AM + the late afternoon/
early PM)

• May discontinue without tapering dose

clonidine HCl Kapvay Rx 0.1mg ext-rel tabs 6–17yrs: 0.2mg twice daily

• Swallow whole

• Titrate by response

• Withdraw gradually by 0.1mg/day at 3−7 day intervals

dextro
amphetamine sulfate
CII 5mg, 10mg scored tabs usually 40mg/day in 2−3 divided doses

• Give in the AM and then 1−2 more doses 4−6hrs apart

Dexedrine Spansule CII 5mg, 10mg, 15mg sust-rel caps 6–17yrs: 40mg/day

• Avoid late evening doses

Zenzedi CII 2.5mg, 5mg, 7.5mg, 10mg, 15mg, 20mg, 30mg tabs ≥3yrs: usually 40mg/day in 2–3 divided doses

• Give first dose upon awakening and then 1–2 more doses 4–6hrs apart

• Avoid late evening doses

dexmethyl
phenidate HCl
Focalin CII 2.5mg, 5mg, 10mg tabs ≥6yrs: 20mg/day

• Give twice daily at least 4hrs apart

• Single isomer methylphenidate product (use 1/2 of racemic methylphenidate dose initially)

Focalin XR CII 5mg, 10mg, 15mg, 20mg, 25mg, 30mg, 35mg, 40mg ext-rel caps 6–17yrs: 30mg/day
≥18yrs: 40mg/day

• Give once daily in the AM

• May sprinkle contents on applesauce and swallow without chewing beads

guanfacine Intuniv Rx 1mg, 2mg, 3mg, 4mg  ext-rel tabs 6–12yrs: 4mg/day
13–17yrs: 7mg/day

• Swallow whole with water, milk, or other liquid

• Do not give with high‑fat meals

• Withdraw gradually by 1mg every 3−7days

lisdexam
fetamine dimesylate
Vyvanse CII 10mg, 20mg, 30mg, 40mg, 50mg, 60mg, 70mg (caps only) caps, chew tabs ≥6yrs: 70mg/day

• Give once daily in the AM. Do not subdivide a single dose.

• Caps: swallow whole or may open and mix/dissolve contents in yogurt, water, or orange juice; take immediately

• Chew tabs: chew thoroughly before swallowing

metham
phetamine HCl
Desoxyn CII 5mg tabs ≥6yrs: usually 20−25mg daily in two divided doses

• Give once or twice daily 30min before meals

• May increase at weekly intervals

methylphen
idate
Cotempla XR-ODT CII 8.6mg, 17.3mg, 25.9mg ext-rel orally disintegrating tabs 6–17yrs: 51.8mg/day

• Give once daily in the AM

• Place on tongue and allow to disintegrate

• May titrate in increments of 8.6–17.3mg weekly

Daytrana CII 10mg, 15mg, 20mg, 30mg trans
dermal patches

• Apply patch to hip 2hrs before desired effect, remove 9hrs after application; may remove earlier if shorter duration of effect or late day side effect appears

• May titrate dose at 1wk intervals

methylphen
idate HCl
CII 5mg tabs 60mg/day in divided doses

• Give preferably 30−45min before meals

10mg, 20mg ext-rel tabs
10mg, 20mg scored tabs
2.5mg, 5mg, 10mg chew tabs 60mg/day in divided doses

• Give before breakfast and lunch

Adhansia XR CII 25mg 35mg, 45mg*, 55mg, 70mg, 85mg ext-rel caps Children: 85mg/day
Adults: 100mg/day

• Give once daily in the AM

• May titrate by 10–15mg at intervals of ≥5 days

• May sprinkle contents on applesauce/yogurt and swallow immediately without chewing beads

Aptensio XR CII 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg ext-rel caps ≥6yrs: 60mg/day

• Give once daily in the AM

• May titrate in increments of 10mg/day weekly

• May sprinkle contents on applesauce and swallow without chewing beads

Concerta CII 18mg, 27mg, 36mg, 54mg ext-rel tabs (with immediate-release outer coating) 6−12yrs: 54mg/day
13−17yrs: 72mg/day or 2mg/kg/day (whichever is less)
≥18yrs: 72mg/day

• Give once daily in the AM

Jornay PM CII 20mg, 40mg, 60mg, 80mg, 100mg ext-rel caps ≥6yrs: 100mg/day

• Give once daily in the PM (between 6:30–9:30)

• May titrate in 20mg increments weekly

• May sprinkle contents on applesauce and swallow without chewing beads

Metadate CD CII 10mg, 20mg, 30mg, 40mg, 50mg, 60mg ext-rel caps (containing immediate and ext‑rel beads) ≥6yrs: 60mg/day

• Give once daily in the AM before breakfast

• May sprinkle contents on applesauce and swallow without chewing beads

Methylin Oral Solution CII 5mg/
5mL, 10mg/
5mL
oral soln ≥6yrs: 60mg/day in divided doses

• Give preferably 30−45min before meals

Quillichew ER CII 20mg, 30mg, 40mg ext-rel chew tabs ≥6yrs: 60mg/day

• Give once daily in the AM

• May titrate in increments of 10mg, 15mg, or 20mg

Quillivant XR CII 5mg/
 
mL
ext-rel oral susp ≥6yrs: 60mg/day

• Give once daily in the AM

• Shake bottle vigorously for ≥10sec before use

• May increase by 10–20mg weekly

Ritalin CII 5mg tabs ≥6yrs: 60mg/day

• Give before breakfast and lunch

10mg, 20mg scored tabs  
Ritalin LA CII 10mg, 20mg, 30mg, 40mg ext-rel caps (half as immediate-release, half as e‑c delayed-release beads) ≥6yrs: 60mg/day

• Give once daily in the AM

• May sprinkle contents on applesauce and swallow without chewing beads

mixed dextro
amphetamine/
amphetamine salts
CII 5mg, 7.5mg, 10mg, 12.5mg, 15mg, 20mg, 30mg double-scored tabs usually 40mg/day in 2−3 divided doses

• Give in AM and 4−6hrs apart

Adderall XR CII 5mg, 10mg, 15mg, 20mg, 25mg, 30mg ext-rel caps6–12yrs: 30mg/day

• Give once daily in the AM upon awakening

• May sprinkle contents on applesauce and swallow without chewing beads

Mydayis CII 12.5mg, 25mg, 37.5mg, 50mg ext-rel caps 13–17yrs: 25mg/day 18–55yrs: 50mg/day

• Give once daily in the AM

• May increase by 12.5mg at weekly intervals

• May sprinkle contents on applesauce and swallow without chewing beads

serdexmethyl
phenidate/ dexmethyl
phenidate
Azstarys CII 26.1mg/
5.2mg, 39.2mg/
7.8mg, 52.3mg/
10.4mg
caps ≥6yrs: 52.3mg/
10.4mg daily

• Give once daily in the AM

• May sprinkle contents into 50mL of water or over 2 tablespoons of applesauce and consume immediately

viloxazine Qelbree Rx 100mg, 150mg, 200mg ext-rel caps 6–17yrs: 400mg/day

• Give once daily with or without food

• May sprinkle contents on applesauce and swallow without chewing beads

NOTES

*Contains tartrazine
Not an inclusive list of medications, official indications, or dosing information. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. Use lowest effective dose. Avoid late evening doses. Re‑evaluate periodically; improvement may be sustained when the drug is either temporarily or permanently discontinued. If paradoxical aggravation of symptoms or other adverse effects occur, the dose should be reduced or discontinued.

(Rev. 8/2021)