In patients with anxiety and depression, low-strength evidence of a possible modest benefit was seen in 4 trials conducted more than 40 years ago and in one recent trial compared with sham treatments.
Gabapentinoids are increasingly being used for almost any type of pain. U.S. prescribing data support this, with gabapentin being the 10th most commonly prescribed medication in 2016.
The researchers identified an additional 24 published studies and 25 unpublished studies, since the last completed systematic review of 57 eligible studies.
The therapeutic efficacy of pregabalin in treating two types neuropathic pain (NeP) is not influenced by concomitant NeP medications, according to new research published in the journal Pain Physician.
For patients with fibromyalgia (FM), coenzyme Q10 (CoQ10) supplementation is associated with improvement in clinical symptoms, according to a letter to the editor published online in CNS Neuroscience & Therapeutics.
Patients with fibromyalgia syndrome (FMS) have high prevalence of anti-thyroid-stimulating hormone (TSH) receptor antibody (TRAb), according to a study published in the International Journal of Rheumatic Diseases.
Pfizer announced positive Phase 3 study data that evaluated Lyrica (pregabalin) capsules and oral solution as adjunctive therapy for pediatric epilepsy patients aged 4-16 years with partial onset seizures.
Tonix Pharmaceuticals announced preliminary data from the Phase 3 AFFIRM study evaluating TNX-102 SL (cyclobenzaprine HCl sublingual tablets) for the treatment of fibromyalgia.
Patients with fibromyalgia syndrome (FMS) with higher self-regulatory fatigue (SRF) have lower quality of life (QoL), according to a study published online in Pain Practice.
The European League Against Rheumatism (EULAR) has published updated recommendations on the management of fibromyalgia in the Annals of the Rheumatic Diseases.
Treatment with quetiapine may be considered for a limited duration (4-12 weeks) to reduce pain, sleep problems, depression, and anxiety in fibromyalgia patients with major depression, data from a Cochrane review has shown.
Pregabalin, a drug often used for anxiety, pain, and other neurologic disorders, may be linked to a higher risk of major birth defects, researchers reported in a Neurology study.
A combination of the anticonvulsant pregabalin and the antidepressant duloxetine may help improve pain relief, physical function, and overall quality of life in patients with fibromyalgia.
Combining pregabalin and paroxetine can increase tolerability and reduce depressive symptoms associated with fibromyalgia, a new controlled, randomized study has suggested.
A new guideline to help clinicians provide optimal pain management for patients following surgery has been released by The American Pain Society.
A new study suggests that opioid prescriptions for patients with neuropathic pain (NeP) may not improve their physical function or disability.