ESC 2017

Does Lowering LDL-C to Ultra-Low Levels Provide Additional Benefit?

By September 01, 2017

The researchers observed these endpoints according to degree of LDL cholesterol reduction after 1 month of treatment.

CABG vs. PCI in Patients with Type 1 Diabetes and Multivessel Disease

August 30, 2017

Compared with CABG, PCI was associated with similar risks of all-cause mortality, and with elevated risks of coronary heart disease mortality, myocardial infarction, and repeat revascularization.

Apixaban Compared to Standard Care in NVAF Patients Undergoing Cardioversion

By August 30, 2017

This is an investigational use for Eliquis.

Does Oxygen Therapy Reduce Mortality in Suspected Acute MI?

August 30, 2017

Routine use of supplemental oxygen does not reduce one-year all-cause mortality versus ambient air

Statins and Breast Cancer: What's the Link?

By August 29, 2017

Researchers concluded that the use of statins is the likely cause of this diagnosis appearing to be beneficial against breast cancer development and subsequent death.

Is There an Ideal BP Target? Analysis Says It May Vary

By August 29, 2017

After adjusting for age and gender, patients randomized to the aggressive treatment arm demonstrated triple the risk of mortality from any cause vs. patients who received less intense treatment (4.9% vs. 1.7%, hazard ratio [HR] 3.12, 95% CI: 1.00-9.69; P=0.012).

Spironolactone and Amiloride Effective in Drug-Resistant Hypertension

By August 29, 2017

Several sub-studies investigated the superior efficacy of spironolactone in RHTN and whether there was potential benefit with amiloride in the same population.

Clinical Benefit of Lowering LDL-C May Depend on How It Is Lowered

August 29, 2017

Change in apoB levels may be better predictor of clinical response than LDL-C, HDL-C levels

Coffee Consumption Linked to Reduced Mortality Risk

August 29, 2017

Four cups a day could reduce risk by 64 percent, researchers say

For STEMI Patients, Mineralocorticoid Antagonists May Up Survival

By August 29, 2017

MRAs such as spironolactone and eplerenone are "still underused in routine clinical practice" but can be effective in countering the harms of high aldosterone levels, explained study author Professor Farzin Beygui, MD, PhD.

Bivalirudin Compared with Heparin Monotherapy Among Patients Undergoing PCI

August 29, 2017

Researchers enrolled patients with ST-segment elevation myocardial infarction (STEMI) or non-STEMI (NSTEMI) who were undergoing PCI and receiving a potent P2Y12 inhibitor to receive bivalirudin or heparin during PCI.

REVEAL AF Study Shows Substantial Incidence of Previously Undiagnosed A-fib

August 29, 2017

In new study using insertable cardiac monitors, rate of AF detection was 40 percent at 30 months

Increases in BP, Hypertension Incidence Linked to Certain NSAIDs

By August 28, 2017

The PRECISION-ABPM study included 444 patients (408 with osteoarthritis; 36 RA) who had evidence of, or were at increased risk for, coronary artery disease.

Bleeding Risk Reduced with Dabigatran Dual Tx vs. Warfarin Triple Tx

By August 28, 2017

The primary safety endpoint was defined as time to major bleeding events and clinically relevant non-major bleeding events when compared to triple therapy with warfarin.

Canakinumab Tied to Significantly Lower Incidence of Recurrent CV Events

August 28, 2017

150-mg dose met prespecified threshold for significance for primary and secondary end points

Risk of MACE Significantly Lower with Rivaroxaban Plus Aspirin

August 28, 2017

Primary outcome for fewer patients receiving rivaroxaban plus aspirin, but more major bleeding