Select therapeutic use:
Indications for ENDARI:
To reduce acute complications of sickle cell disease.
Adults and Children:
<5yrs: not established. Mix each dose in 8oz (240mL) of cold or room temperature drink (eg, water, milk, apple juice) or 4–6oz of food (eg, applesauce, yogurt) prior to ingestion; complete dissolution not required. ≥5yrs (<30kg): 5g twice daily; (30–65kg): 10g twice daily; (>65kg): 15g twice daily.
Pregnancy. Nursing mothers.
Constipation, nausea, headache, abdominal pain, cough, pain in extremity, back pain, chest pain.