In their article, the authors report on two patients who used kratom to self-treat their chronic pain after they could no longer receive opioid analgesics from healthcare providers.
The researchers identified 3 asthma-related intubations (2 in the inhaled-glucocorticoid group, 1 in the combination therapy group) and 2 asthma-related deaths (both in the combination-therapy group) in 4 patients among the 36,010 patients in the intention-to-treat study.
To shed further light on the study's implications, MPR interviewed lead author Anupam B. Jena, MD, PhD, Ruth L. Newhouse Associate Professor, Harvard Medical School, Boston, MA.
Informed consent, privacy, and justice concerns are 3 issues that should be addressed before the use of online genealogy data in criminal cases becomes widely adopted.
Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).
Kymriah uses the 4-1BB costimulatory domain in its chimeric antigen receptor to enhance cellular expansion and persistence.
The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.
This is the first device authorized for marketing that provides a screening decision without the need for clinician interpretation.
When the central layer of the sensor comes in contact with 1 of the pre-defined nutrients (in the current case salt, glucose or alcohol), it's electrical properties change and the sensor absorbs and transmits a different spectrum of radio waves with varying intensity.
Suppression of follicle stimulating hormone and luteinizing hormone was reported for all subjects in the P400mg group and 12 of 13 subjects in the C400mg group. No significant change was seen in mood.
Around 1,200 security workers at the winter Olympics in PyeongChang are being kept in their rooms due to a norovirus outbreak that has already sickened 41 people.
There was also a decrease in mean systolic blood pressure (BP) from 137 to 130mmHg and in diastolic BP from 82 to 75 mm Hg (both P<0.0001).
Those with moderate-to-severe deficiency (iodine-creatinine ratios <50 μg/g) had a 46% reduction in fecundity versus those whose iodine-creatinine ratios were in the adequate range (adjusted fecundability odds ratio of becoming pregnant per cycle, 0.54).
A patient is misdiagnosed twice and doesn't get a doctor recommended blood test, the patient subsequently died. Was there contributory negligence on behalf of the patient?
The authors concluded, "The findings suggest that ibuprofen-acetaminophen is a reasonable alternative to opioid management of acute extremity pain due to sprain, strain, or fracture."
The panel - made up of nearly 100 physicians and scientists - debated and whittled down over 150 nominations to decide upon the final 10.
Receipt of red blood cell transfusion from ever-pregnant donor tied to increased risk for males.
Researchers analyzed data from >60,000 physician respondents who are based in the largest 50 metropolitan areas and compared this with U.S. census data.
A total of 703 abortion facilities in the U.S. and 94 in Canada were surveyed to estimate the prevalence of medication abortion practices and to compare the regional differences.
The case involved a 69-year old patient with paranoid schizophrenia who was brought to the emergency department following violent behavior against the staff at the nursing facility he resided in.
Research on whether aspirin (which has both anti-inflammatory and anti-atherosclerotic properties) has an impact on depression has been limited.
The use of complementary and alternative medicine (CAM) specifically for the treatment of migraine and headache is "relatively low" in the U.S.