Severe Acute Respiratory Distress Syndrome Following HCTZ Administration

By October 31, 2018

"One of the most commonly prescribed antihypertensives, HCTZ is associated with rare cases of pulmonary edema, which typically develop within minutes to hours of the initial dose of the medication," the study authors stated.

Labeling Mix-Up Prompts Recall of HCTZ Bottles That May Contain Another Diuretic

By August 29, 2018

To date, there have been no reports of any adverse events related to this recall.

Many AKI Reports in FAERS Linked to Drugs Not Recognized as Nephrotoxic

By June 12, 2018

According to the authors, this is the first study to identify medications most commonly reported for a specific adverse reaction using this database.

FDA-Approved Spironolactone Oral Suspension Now Available

By October 30, 2017

First FDA-approved oral liquid dosage form of the potassium-sparing diuretic spironolactone.

New Cardiovascular Safety Warnings Added to All NSAIDs

By May 13, 2016

The lowest effective dose for the shortest duration possible should be used to minimize the potential risk.

Par Approved for Generic Sodium Edecrin

By August 04, 2015

Par Pharmaceuticals announced that the Food and Drug Administration (FDA) has approved Ethacrynate Sodium for Injection, the first generic version of Aton Pharma's Sodium Edecrin.

HCTZ Bottles Recalled After Discovery of Blood Thinner Tablet

July 31, 2015

Unichem Pharmaceuticals issued a voluntary nationwide recall of Hydrochlorothiazide 25mg tablets after the discovery of a Clopidogrel tablet in a bottle.

One in Three Prefer Earlier Death to Daily Pill

February 04, 2015

One of three survey respondents rejected the idea even if it meant a shorter life

Spironolactone + Antibiotic Combo May Up Sudden Death Risk

February 03, 2015

Taking spironolactone alongside the antibiotic trimethoprim-sulfamethoxazole can cause blood potassium to rise to potentially life-threatening levels.

Spironolactone After Heart Failure: Assessing 30-Day Outcomes

August 28, 2014

Research indicates that spironolactone may reduce rehospitalizations and 30-day mortality in patients with acute heart failure (AHF).

New Flexbumin 5% Strength Approved

August 04, 2014

Baxter announced that the FDA has approved Flexbumin (albumin [human]) 5% solution for the treatment of hypovolemia, hypoalbuminemia due to general causes, burns, and for use during cardiopulmonary bypass surgery as a component of the pump prime.

Rx Adherence Up for Hispanics Post-Medicare Part D Launch

June 04, 2014

Hispanics became much more likely to take their heart medicines after Medicare's prescription drug benefit plan was launched in 2006, but there was only a small increase seen among black patients.

ω-3 Fatty Acids, Xanthophylls Don't Cut CVD Risk

March 21, 2014

Findings show no reduction in risk in cohort of older adults with age-related macular degeneration

Heart Failure and LUTS: Managing Competing Drugs

March 14, 2014

An increasing number of people suffer from conditions typically associated with aging, including heart failure (HF) and lower urinary tract symptoms (LUTS).

USPSTF: Evidence Lacking for Vitamin Prevention of CVD, CA

February 25, 2014

The USPSTF has found that insufficient evidence to evaluate the benefits and harms of multivitamins and most single- or paired-nutrient supplements for the prevention of cardiovascular disease and cancer.

ACC Calls for Patient-Centered Approach in Cardiac Imaging

February 24, 2014

Quality, patient outcomes, and costs must all be assessed in determining the appropriateness of noninvasive cardiovascular imaging.

Getting to the Heart of the Matter: A Review of Potential Drug Interactions With Cardiac Medications

February 10, 2014

Cardiac drug interactions make up almost 25% of all preventable adverse drug reactions.

Patients Are 'Myth'-Informed About Their Risk of Cancer

February 04, 2014

Fewer than half of Americans are aware that body weight and physical activity affect cancer risk.

Study IDs Cardiovascular Risk for 'Silent' Adrenal Tumors

January 30, 2014

Patients with adrenal tumors of intermediate phenotype or subclinical Cushing's syndrome are at increased risk of cardiovascular events and mortality compared to those with stable non-secreting adrenal incidentalomas.

First Trimester Critical for Cardiovascular Risk Factors

January 28, 2014

First trimester fetal growth restriction correlates with an adverse cardiovascular risk profile in childhood.

Pulmonary Congestion Predicts Death, Cardiac Events in ESRD

March 01, 2013

Pulmonary congestion can predict risk of death and cardiac events in patients with end-stage renal disease undergoing dialysis.

PCI Linked to Increased Platelet Reactivity

October 12, 2012

Patients with coronary artery disease who receive percutaneous coronary intervention (PCI) have increased platelet reactivity after the procedure despite antiplatelet therapy.

Positive Predictive Value of Treadmill Test Varies in Women

October 05, 2012

The positive predictive value (PPV) of the exercise treadmill test (ETT) for coronary artery disease (CAD) in women is altered significantly by age and certain exercise responses.

Early Prophylactic Tx Beneficial for Hypertrophic Cardiomyopathy

September 10, 2012

Beta blockers (BBs) are effective as an early prophylactic pharmacologic treatment for patients with mild hypertrophic cardiomyopathy (HC) who have exercise-induced left ventricular outflow tract (LVOT) obstruction.

Exercise, Drugs Compared for Depression Tx in CHD Patients

August 03, 2012

In patients with coronary heart disease, aerobic exercise and the antidepressant sertraline are both associated with reduced depressive symptoms when compared to placebo, and they both tend to improve heart rate variability.

Early Mediterranean Diet Benefits Arteries in Adulthood

July 31, 2012

Adherence to a Mediterranean dietary pattern in early life is associated with lower arterial stiffness in adulthood.

Nebivolol Better Preserves Exercise Performance at Altitude

July 16, 2012

Under high altitude (HA) hypoxemia conditions, exercise performance seems to be better preserved with nebivolol than carvedilol.

Diagonal Ear Lobe Crease Tied to Coronary Artery Disease

May 16, 2012

Diagonal ear lobe crease (DELC) is independently and significantly associated with the prevalence, extent, and severity of coronary artery disease (CAD).

SCAI: Ixmyelocel-T Studied for Dilated Cardiomyopathy

May 14, 2012

For patients with dilated cardiomyopathy, treatment with an autologous bone marrow-derived, expanded multi-cell product, ixmyelocel-T, is well tolerated and associated with improved symptoms at one year.

Ibuprofen Cuts Incidence, Severity of Altitude Sickness

March 23, 2012

For healthy adults ascending from low to high altitude, ibuprofen effectively reduces the incidence and severity of acute mountain sickness, compared with placebo.