Phase 2 study of FV-100 for herpes zoster

Inhibitex announced that it has initiated a Phase 2 trial with FV-100, its once-daily, oral antiviral compound in development for the treatment of herpes zoster (shingles). This trial is a well-controlled, double-blind study evaluating FV-100 against an active control (valacyclovir) in approximately 350 patients who are ≥50 years of age.  Trial objectives include the evaluation of the safety and therapeutic benefit of FV-100 in reducing: the severity and duration of shingles-related acute pain; the incidence of post herpetic neuralgia (PHN); the time to lesion healing; and the use of concomitant pain medications.

FV-100 is an orally-available bicyclic nucleoside analogue that inhibits replication of varicella zoster virus (VZV).

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