Zzzquil Liquid

  • Sleep-wake disorders

Zzzquil Liquid Generic Name & Formulations

General Description

Diphenhydramine HCl 50mg; per 30mL; warming berry flavor; contains sodium 23mg/30mL and alcohol.

Pharmacological Class

Hypnotic (anticholinergic).

See Also

How Supplied

Liquicaps—12, 24, 48; Liq—6oz, 12oz

Zzzquil Liquid Indications


Relief of occasional sleeplessness.

Zzzquil Liquid Dosage and Administration


50mg at bedtime as needed.


Not recommended.

Zzzquil Liquid Contraindications

Not Applicable

Zzzquil Liquid Boxed Warnings

Not Applicable

Zzzquil Liquid Warnings/Precautions


Asthma. Emphysema. Chronic bronchitis. Glaucoma. Cardiovascular disease. GI or GU obstruction. Reevaluate if no response or symptoms persist after 2 weeks. Pregnancy. Nursing mothers.

Zzzquil Liquid Pharmacokinetics

See Literature

Zzzquil Liquid Interactions


Potentiates CNS depression with alcohol, other CNS depressants. Concomitant other diphenhydramine products (including topicals): not recommended. Additive effects with other antihistamines, anticholinergics, sedatives, tranquilizers or other nighttime cold/fu products (eg, NyQuil); avoid.

Zzzquil Liquid Adverse Reactions

Adverse Reactions

Drowsiness, dizziness, anticholinergic effects, paradoxical excitement.

Zzzquil Liquid Clinical Trials

See Literature

Zzzquil Liquid Note

Not Applicable

Zzzquil Liquid Patient Counseling

See Literature