Zyrtec-d 12 Hour

  • Cough and cold

Zyrtec-d 12 Hour Generic Name & Formulations

General Description

Cetirizine HCl 5mg, pseudoephedrine HCl 120mg; ext-rel tabs.

Pharmacological Class

Antihistamine + sympathomimetic.

How Supplied

Tabs—12, 24

Zyrtec-d 12 Hour Indications


Seasonal or perennial allergic rhinitis with nasal congestion.

Zyrtec-d 12 Hour Dosage and Administration


Swallow whole. 1 tab twice daily. Hepatic or renal impairment (CrCl ≤31mL/min): 1 tab once daily.


Not recommended.

Zyrtec-d 12 Hour Contraindications


Hydroxyzine sensitivity. Narrow-angle glaucoma. Urinary retention. Severe hypertension or coronary artery disease. During or within 14 days of MAOIs.

Zyrtec-d 12 Hour Boxed Warnings

Not Applicable

Zyrtec-d 12 Hour Warnings/Precautions


Hypertension. Diabetes. Ischemic heart disease. Increased intraocular pressure. Hyperthyroidism. GI or GU obstruction. Seizure disorders. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Zyrtec-d 12 Hour Pharmacokinetics

See Literature

Zyrtec-d 12 Hour Interactions


See Contraindications. Pseudoephedrine: Antagonizes antihypertensives. Increased ectopic pacemaker activity with digitalis. Avoid other sympathomimetics, alcohol, other CNS depressants.

Zyrtec-d 12 Hour Adverse Reactions

Adverse Reactions

Insomnia, dry mouth, somnolence, dizziness; rarely: elevated liver enzymes.

Zyrtec-d 12 Hour Clinical Trials

See Literature

Zyrtec-d 12 Hour Note

Not Applicable

Zyrtec-d 12 Hour Patient Counseling

See Literature