Cough and cold:

Indications for ZYRTEC-D 12 HOUR:

Seasonal or perennial allergic rhinitis with nasal congestion.


Swallow whole. 1 tab twice daily. Hepatic or renal impairment (CrCl ≤31mL/min): 1 tab once daily.


Not recommended.


Hydroxyzine sensitivity. Narrow-angle glaucoma. Urinary retention. Severe hypertension or coronary artery disease. During or within 14 days of MAOIs.


Hypertension. Diabetes. Ischemic heart disease. Increased intraocular pressure. Hyperthyroidism. GI or GU obstruction. Seizure disorders. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Pharmacologic Class:

Antihistamine + sympathomimetic.


See Contraindications. Pseudoephedrine: Antagonizes antihypertensives. Increased ectopic pacemaker activity with digitalis. Avoid other sympathomimetics, alcohol, other CNS depressants.

Adverse Reactions:

Insomnia, dry mouth, somnolence, dizziness; rarely: elevated liver enzymes.

How Supplied:

Tabs—12, 24