Zinplava

— THERAPEUTIC DISORDERS TREATED —
  • Diarrhea

Zinplava Generic Name & Formulations

General Description

Bezlotoxumab 25mg/mL; soln for IV infusion after dilution; preservative-free.

Pharmacological Class

Human IgG1 monoclonal antibody.

How Supplied

Single-dose vial (40mL)—1

Manufacturer

Generic Availability

NO

Zinplava Indications

Indications

To reduce recurrence of Clostridioides difficile infection (CDI) in patients who are receiving antibacterial drug treatment of CDI and are at high risk for CDI recurrence.

Limitations of Use

Not for treating CDI. Use only in conjunction with antibacterial drug treatment of CDI.

Zinplava Dosage and Administration

Adult

Infuse over 60mins. ≥18yrs: a single dose of 10mg/kg.

Children

<18yrs: not established.

Zinplava Contraindications

Not Applicable

Zinplava Boxed Warnings

Not Applicable

Zinplava Warnings/Precautions

Warnings/Precautions

History of CHF. Pregnancy. Nursing mothers.

Zinplava Pharmacokinetics

See Literature

Zinplava Interactions

Zinplava Adverse Reactions

Adverse Reactions

Nausea, pyrexia, headache, infusion-related reactions; heart failure.

Zinplava Clinical Trials

See Literature

Zinplava Note

Not Applicable

Zinplava Patient Counseling

See Literature