Zinplava Generic Name & Formulations
Mechanism of Action
Bezlotoxumab, a human monoclonal antibody, inhibits the binding of toxin B and prevents its effects on mammalian cells. Bezlotoxumab does not bind to C. difficile toxin A.
Limitations of Use
Zinplava Dosage and Administration
Adults and Children
<1yr: not established. Infuse over 60mins. ≥1yr: a single dose of 10mg/kg.
Zinplava Boxed Warnings
Mean volume of distribution: 7.33 L.
Half-life: ~19 days. Geometric mean clearance: 0.317 L/day.
Zinplava Adverse Reactions
Zinplava Clinical Trials
Zinplava Patient Counseling