Zinplava Generic Name & Formulations
Bezlotoxumab 25mg/mL; soln for IV infusion after dilution; preservative-free.
Human IgG1 monoclonal antibody.
Single-dose vial (40mL)—1
To reduce recurrence of Clostridioides difficile infection (CDI) in patients who are receiving antibacterial drug treatment of CDI and are at high risk for CDI recurrence.
Limitations of Use
Not for treating CDI. Use only in conjunction with antibacterial drug treatment of CDI.
Zinplava Dosage and Administration
Infuse over 60mins. ≥18yrs: a single dose of 10mg/kg.
<18yrs: not established.
Zinplava Boxed Warnings
History of CHF. Pregnancy. Nursing mothers.
Zinplava Adverse Reactions
Nausea, pyrexia, headache, infusion-related reactions; heart failure.
Zinplava Clinical Trials
Zinplava Patient Counseling