Indications for ZILXI:

Inflammatory lesions of rosacea.

Limitations of Use:

Not been evaluated in the treatment of infections.


Apply at the same time each day ≥1hr before bedtime. Apply a thin layer onto affected area(s) of the face; repeat as needed. Avoid bathing, showering or swimming for ≥1hr after application.


Not established.


Not for oral, ophthalmic, or intravaginal use. Monitor for visual disturbances prior to initiation. History of intracranial hypertension. Overweight women. Avoid sunlight or UV light; discontinue at 1st sign of sunburn. Discontinue if serious skin reactions (eg, Stevens Johnson syndrome, erythema multiforme, DRESS syndrome) or superinfection develop. Hepatic or renal impairment. Product is flammable. Pregnancy. Nursing mothers: not recommended.

Pharmacologic Class:

Tetracycline antibiotic.


Avoid concomitant penicillins, isotretinoin. May need to reduce concomitant anticoagulant dose. May interfere with fluorescence test.

Adverse Reactions:

Diarrhea; teeth discoloration, delayed skeletal development, intracranial hypertension, CNS effects, C. difficile-associated diarrhea, increased BUN, hepatotoxicity, renal toxicity, photosensitivity, skin/hypersensitivity reactions (may be severe), hyperpigmentation, autoimmune syndromes (eg, lupus-like syndrome, serum sickness; discontinue if symptoms occur).

Generic Availability:


How Supplied:


Pricing for ZILXI

30g of 1.5% can of foam (Qty: 1)
Appx. price $504