Ziana

— THERAPEUTIC DISORDERS TREATED —
  • Acne

Ziana Generic Name & Formulations

General Description

Clindamycin phosphate 1.2%; tretinoin 0.025%; gel.

Pharmacological Class

Lincosamide + retinoid.

How Supplied

Gel—2g, 30g, 60g

Ziana Indications

Indications

Acne vulgaris.

Ziana Dosage and Administration

Adult

Apply thin film to clean, dry face once daily at bedtime.

Children

Not recommended.

Ziana Contraindications

Contraindications

Regional enteritis. Ulcerative colitis. History of antibiotic-associated colitis.

Ziana Boxed Warnings

Not Applicable

Ziana Warnings/Precautions

Warnings/Precautions

Sunburn (allow to heal before using). Avoid sun, UV light, eyes, mouth, angles of nose, mucous membranes. Discontinue if significant diarrhea occurs. Increased irritation in extreme weather. Pregnancy (Cat.C). Nursing mothers: not recommended.

Ziana Pharmacokinetics

See Literature

Ziana Interactions

Interactions

Avoid erythromycin. Additive irritation with other topical products (eg, alcohol, drying agents, lime). May potentiate neuromuscular blockers. Caution with other photosensitizers (eg, tetracyclines, quinolones).

Ziana Adverse Reactions

Adverse Reactions

Erythema, scaling, itching, burning, stinging, nasopharyngitis, throat pain, dry skin, cough, sinusitis; rare: diarrhea, colitis.

Ziana Clinical Trials

See Literature

Ziana Note

Not Applicable

Ziana Patient Counseling

See Literature