Xylocaine Mpf Injection

  • Anesthetics

Xylocaine Mpf Injection Generic Name & Formulations

General Description

Lidocaine HCl 5mg/mL, 10mg/mL, 15mg/mL, 20mg/mL, 40mg/mL; soln.

Pharmacological Class

Local anesthetic.

How Supplied

Multi-dose vial (10mL, 20mL, 50mL)—25; MPF plastic ampules (10mL, 20mL)—5; MPF single-dose vial (2mL, 5mL, 50mL)—25; MPF single-dose vial (30mL)—5, 25


Xylocaine Mpf Injection Indications


Local or regional anesthesia for infiltration and nerve block (see full labeling).

Xylocaine Mpf Injection Dosage and Administration


See full labeling for recommended dosages based on procedures. Epidural anesthesia: administer test dose first; monitor for CNS or cardiovascular toxicity. For all procedures: Max total dose: 4.5mg/kg not to exceed 300mg; epidural or caudal anesthesia should not be administered at intervals <90 minutes. Paracervical block: max 200mg total per 90 minute period. Elderly, debilitated, acutely ill (eg, cardiac or liver disease): reduce dose.


<3yrs: individualize based on weight and age. >3yrs: usual max dose: 1.5–2mg/lb. See full labeling for dosages specific to procedures.

Xylocaine Mpf Injection Contraindications

Not Applicable

Xylocaine Mpf Injection Boxed Warnings

Not Applicable

Xylocaine Mpf Injection Warnings/Precautions


To be administered under the supervision of experienced clinicians. Have intubation, artificial respiration, oxygen therapy and reversal agents available. Risk of methemoglobinemia (esp. in G6PD deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants <6 months of age, concurrent exposure to oxidizing agents or metabolites); monitor. Intra-articular infusions: not recommended. Avoid intravascular inj. Avoid methylparaben with spinal or epidural anesthesia. Monitor cardiovascular and respiratory vital signs. Severe shock. Heart block. Neurological disease. Spinal deformities. Septicemia. Severe hypertension. Hepatic disease. Impaired cardiovascular function. Malignant hyperthermia. Head and neck administration. Labor & delivery: see full labeling. Pregnancy (Cat.B). Nursing mothers.

Xylocaine Mpf Injection Pharmacokinetics

See Literature

Xylocaine Mpf Injection Interactions


Increased risk of methemoglobinemia when concurrently exposed to nitrates/nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, others. Additive effects with other products containing local anesthetics.

Xylocaine Mpf Injection Adverse Reactions

Adverse Reactions

CNS effects (eg, lightheadedness, confusion), cardiovascular effects (eg, bradycardia, hypotension, cardiovascular collpase), hypersensitivity reactions, headache, backache, nausea, increased creatinine phosphokinase.

Xylocaine Mpf Injection Clinical Trials

See Literature

Xylocaine Mpf Injection Note

Not Applicable

Xylocaine Mpf Injection Patient Counseling

See Literature