Xopenex Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Soln 0.31mg/3mL, 0.63mg/3mL, 1.25mg/3mL—24 vials; 1.25mg/0.5mL—30 vials
Manufacturer
Generic Availability
YES
Xopenex Indications
Indications
Xopenex Dosage and Administration
Adult
Initially 0.63mg by nebulization 3 times daily at 6–8hr intervals; may increase to 1.25mg 3 times daily.
Children
<6yrs: not established. 6–11yrs: 0.31mg by nebulization 3 times daily; max 0.63mg 3 times daily.
Renal Impairment
Risk of toxic reactions may be greater in patients with impaired renal function as albuterol is substantially excreted by the kidney.
It may be useful to monitor renal function in patients with renal impairment.
Hepatic Impairment
The effect of hepatic impairment on the pharmacokinetics of Xopenex Inhalation Solution has not been evaluated.
Xopenex Contraindications
Not Applicable
Xopenex Boxed Warnings
Not Applicable
Xopenex Warnings/Precautions
Warnings/Precautions
Xopenex Pharmacokinetics
Elimination
The primary route of elimination of albuterol enantiomers is through renal excretion. Less than 20% of the drug is detected in the feces.
Xopenex Interactions
Interactions
Xopenex Adverse Reactions
Adverse Reactions
Xopenex Clinical Trials
Xopenex Note
Not Applicable