Xifaxan 550mg

— THERAPEUTIC CATEGORIES —
  • Colorectal disorders
  • Hepatic encephalopathy

Xifaxan 550mg Generic Name & Formulations

General Description

Rifaximin 550mg; tabs.

Pharmacological Class

Rifamycin.

How Supplied

Tabs—60

Xifaxan 550mg Indications

Indications

Irritable bowel syndrome with diarrhea (IBS-D).

Xifaxan 550mg Dosage and Administration

Adult

≥18yrs: 550mg three times daily for 14 days. Recurrent episodes: can retreat up to two times with the same dosage regimen.

Children

<18yrs: not established.

Xifaxan 550mg Contraindications

Not Applicable

Xifaxan 550mg Boxed Warnings

Not Applicable

Xifaxan 550mg Warnings/Precautions

Warnings/Precautions

Not studied in patients with MELD scores >25 (only 8.6% of patients in the controlled trial had MELD >19). Severe hepatic impairment (Child-Pugh C). Elderly. Pregnancy. Nursing mothers.

Xifaxan 550mg Pharmacokinetics

See Literature

Xifaxan 550mg Interactions

Interactions

Potentiated by P-gp inhibitors (eg, cyclosporine); caution. Monitor INR and PT with warfarin; dose adjustment may be needed.

Xifaxan 550mg Adverse Reactions

Adverse Reactions

Peripheral edema, nausea, dizziness, fatigue, ascites, increased ALT.

Xifaxan 550mg Clinical Trials

See Literature

Xifaxan 550mg Note

Not Applicable

Xifaxan 550mg Patient Counseling

See Literature

Xifaxan 550mg Generic Name & Formulations

General Description

Rifaximin 550mg; tabs.

Pharmacological Class

Rifamycin.

How Supplied

Tabs—60

Xifaxan 550mg Indications

Indications

Reduction in risk of overt hepatic encephalopathy recurrence.

Xifaxan 550mg Dosage and Administration

Adult

≥18yrs: 550mg twice daily.

Children

<18yrs: not established.

Xifaxan 550mg Contraindications

Not Applicable

Xifaxan 550mg Boxed Warnings

Not Applicable

Xifaxan 550mg Warnings/Precautions

Warnings/Precautions

Not studied in patients with MELD scores >25 (only 8.6% of patients in the controlled trial had MELD >19). Severe hepatic impairment (Child-Pugh C). Elderly. Pregnancy. Nursing mothers.

Xifaxan 550mg Pharmacokinetics

See Literature

Xifaxan 550mg Interactions

Interactions

Potentiated by P-gp inhibitors (eg, cyclosporine); caution. Monitor INR and PT with warfarin; dose adjustment may be needed.

Xifaxan 550mg Adverse Reactions

Adverse Reactions

Peripheral edema, nausea, dizziness, fatigue, ascites, increased ALT.

Xifaxan 550mg Clinical Trials

See Literature

Xifaxan 550mg Note

Not Applicable

Xifaxan 550mg Patient Counseling

See Literature

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