Xalatan Generic Name & Formulations
Legal Class
Rx
General Description
Latanoprost 0.005%; oph soln; contains benzalkonium chloride.
Pharmacological Class
Prostaglandin analogue.
How Supplied
Soln—2.5mL
Manufacturer
Generic Availability
YES
Xalatan Indications
Indications
Open-angle glaucoma. Ocular hypertension.
Xalatan Dosage and Administration
Adult
1 drop in the affected eye(s) once daily in the PM.
Children
Not recommended.
Xalatan Contraindications
Not Applicable
Xalatan Boxed Warnings
Not Applicable
Xalatan Warnings/Precautions
Warnings/Precautions
Do not exceed recommended dose (may reduce efficacy). Ocular inflammation. Aphakia. Pseudophakia with torn posterior lens capsule. Risk of macular edema. Contact lenses (remove; may reinsert lenses 15mins after administration). Pregnancy. Nursing mothers.
Xalatan Pharmacokinetics
Absorption
Absorbed through the cornea where the isopropyl ester prodrug is hydrolyzed to the acid form to become biologically active.
Elimination
Renal.Half-life: 17 minutes
Xalatan Interactions
Interactions
Allow at least 5mins between application of other topical oph agents.
Xalatan Adverse Reactions
Adverse Reactions
Blurred vision, burning, stinging, conjunctival hyperemia, foreign body sensation, itching, increased ocular pigmentation (eg, iris, eyelid, eyelashes; may be permanent), punctate keratitis, other eyelash/lid changes, photophobia, upper respiratory tract infection, pain, angina, rash; intraocular inflammation, macular edema (including cystoid macular edema).
Xalatan Clinical Trials
Xalatan Note
Not Applicable
Xalatan Patient Counseling
Cost Savings Program
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