Vowst Generic Name & Formulations
Mechanism of Action
The mechanism of action has not been established.
Prevention of recurrence of Clostridioides difficile infection (CDI) in adults following antibiotic treatment for recurrent CDI.
Limitations of Use
Not for treatment of CDI.
Vowst Dosage and Administration
Complete antibacterial treatment for recurrent CDI 2–4 days prior to intiation. Drink 10oz (296mL) magnesium citrate 1 day prior to and ≥8hrs prior to first dose of Vowst; avoid eating or drinking (except for small amount of water) for ≥8hrs prior to first dose. Take on empty stomach prior to first meal of the day. ≥18yrs: 4 caps once daily for 3 consecutive days.
<18yrs: not established.
Vowst Boxed Warnings
Manufactured from human fecal matter. Risk of transmissible infectious agents. Potential presence of food allergens. Acute allergic reactions. Pregnancy. Nursing mothers.
Avoid concomitant antibiotics.
Vowst Adverse Reactions
Abdominal distension, fatigue, constipation, chills, diarrhea.
Vowst Clinical Trials
Vowst Patient Counseling