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Varivax Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Single-dose vials—10 (w. diluent)
Manufacturer
Generic Availability
NO
Mechanism of Action
Varivax Indications
Indications
Varivax Dosage and Administration
Adult
Give by SC or IM inj. ≥13yrs: 1 dose of 0.5mL at elected date and a 2nd dose of 0.5mL at least 4 weeks later.
Children
<12mos: not established. Give by SC or IM inj. 12mos–12yrs: administer 1st dose of 0.5mL at 12 to 15 months of age but may give anytime through 12yrs of age, then give 2nd dose at 4–6yrs of age.
Varivax Contraindications
Contraindications
Hypersensitivity to gelatin or neomycin. Immunodeficient or immunosuppressed. Active febrile illness with fever >101.3⁰F (>38.5⁰C). Active untreated tuberculosis. During pregnancy or individuals who are planning on becoming pregnant in the next 3 months.
Varivax Boxed Warnings
Not Applicable
Varivax Warnings/Precautions
Warnings/Precautions
Have epinephrine inj (1:1000) available. Defer vaccination if family history of congenital or hereditary immunodeficiency until immunocompetent. Avoid contact with susceptible high-risk individuals for up to 6 weeks after vaccination. HIV-infected: refer to ACIP recommendations. Nursing mothers.
Varivax Pharmacokinetics
See Literature
Varivax Interactions
Interactions
Avoid salicylates in patients (12 months through 17 years of age) for 6 weeks after vaccination. Concomitant administration with immune globulins and other blood products may interfere with the expected immune response; refer to ACIP recommendations. May interfere with tuberculin skin test. Separate by at least 1 month between a dose of a live attenuated measles virus-containing vaccine and Varivax. In children through 12yrs, separate by at least 3 months between 2 doses of a live attenuated varicella virus-containing vaccine and Varivax.
Varivax Adverse Reactions
Adverse Reactions
Fever, inj site reactions, rash; others.
Varivax Clinical Trials
See Literature
Varivax Note
Not Applicable
Varivax Patient Counseling
See Literature
