Diarrhea:
Indications for VANCOCIN:
Clostridioides difficile-associated diarrhea. Enterocolitis due to Staphylococcus aureus.
Adult:
C. difficile-associated diarrhea: 125mg 4 times a day for 10 days. Enterocolitis: 500mg–2g per day in 3–4 divided doses for 7–10 days.
Children:
Both: usually 40mg/kg per day in 3–4 divided doses for 7–10 days; max 2g/day.
Warnings/Precautions:
Renal insufficiency and/or colitis. Inflammatory bowel disorders. Underlying hearing loss. Monitor hearing, blood, renal function. Consider monitoring vancomycin serum concentrations. Elderly. Pregnancy. Nursing mothers.
Pharmacologic Class:
Antibiotic.
Interactions:
Monitor with aminoglycosides, other neurotoxic, nephrotoxic, or ototoxic drugs.
Adverse Reactions:
Nausea, abdominal pain, hypokalemia, drug fever, urticaria, rash (may be serious, eg, Stevens-Johnson syndrome), ototoxicity, nephrotoxicity, eosinophilia, anaphylaxis, blood dyscrasias; rare: interstitial nephritis, vertigo.
Generic Availability:
YES
How Supplied:
Caps—20
