• Benign prostatic hyperplasia/urinary retention

Uroxatral Generic Name & Formulations

General Description

Alfuzosin (as HCl) 10mg; ext-rel tabs.

Pharmacological Class

Alpha-1 blocker.

How Supplied

Tabs—30, 100

Uroxatral Indications


Benign prostatic hyperplasia (BPH).

Limitations of Use

Not for use in children or for the treatment of hypertension.

Uroxatral Dosage and Administration


Swallow whole. Take immediately after same meal each day. 10mg once daily.


Not applicable.

Uroxatral Contraindications


Concomitant potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir). Moderate or severe hepatic impairment.

Uroxatral Boxed Warnings

Not Applicable

Uroxatral Warnings/Precautions


Not for use in women. Discontinue if angina develops or worsens. Severe renal insufficiency (CrCl <30mL/min). Hypotension. Mild hepatic impairment. History of QT interval prolongation. Exclude prostate cancer prior to initiation. Cataract surgery (intraoperative floppy iris syndrome possible).

Uroxatral Pharmacokinetics

See Literature

Uroxatral Interactions


See Contraindications. Do not use with other α-blockers. Increased hypotension with concomitant nitrates, PDE5 inhibitors, other antihypertensives. Potentiates and is potentiated by cimetidine. Potentiates cardiovascular effects of atenolol. Caution with drugs that prolong QT interval.

Uroxatral Adverse Reactions

Adverse Reactions

Dizziness, upper respiratory tract infection, headache, fatigue; postural hypotension, syncope; rare: priapism.

Uroxatral Clinical Trials

See Literature

Uroxatral Note

Not Applicable

Uroxatral Patient Counseling

See Literature