• Acne

Twyneo Generic Name & Formulations

General Description

Tretinoin 0.1%, benzoyl peroxide 3%; crm.

Pharmacological Class

Retinoid + antibacterial/keratolytic.

How Supplied

Crm–50g (pump)

Generic Availability


Twyneo Indications


Acne vulgaris.

Twyneo Dosage and Administration

Adults and Children

<9yrs: not established. ≥9yrs: apply a thin layer to the affected areas once daily on clean, dry skin. Wash hands after application.

Twyneo Contraindications

Not Applicable

Twyneo Boxed Warnings

Not Applicable

Twyneo Warnings/Precautions


Not for oral, ophthalmic or intravaginal use. Avoid eyes, lips, paranasal creases, and mucous membranes. Discontinue immediately if serious hypersensitivity reactions occur. Avoid application to cuts, abrasions, eczematous, or sunburned skin. Minimize exposure to sun or UV light (eg, tanning beds or UVA/B treatment). Discontinue at 1st sign of sunburn. Advise to use moisturizer, reduce frequency of application, or discontinue if skin irritation occurs. Pregnancy. Nursing mothers.

Twyneo Pharmacokinetics

See Literature

Twyneo Interactions

Not Applicable

Twyneo Adverse Reactions

Adverse Reactions

Application site reactions (pain, dryness, exfoliation, erythema, dermatitis, pruritus, irritation); hypersensitivity reactions, skin irritation, photosensitivity.

Twyneo Clinical Trials

See Literature

Twyneo Note

Not Applicable

Twyneo Patient Counseling

See Literature