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Trulance Generic Name & Formulations
Legal Class
Rx
General Description
Plecanatide 3mg; tabs.
Pharmacological Class
Guanylate cyclase-C agonist.
How Supplied
Tabs—30
Manufacturer
Generic Availability
NO
Trulance Indications
Indications
Irritable bowel syndrome with constipation (IBS-C).
Trulance Dosage and Administration
Adult
Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.
Children
<6yrs: contraindicated. 6–<18yrs: avoid.
Trulance Contraindications
Contraindications
Children <6yrs old. Known or suspected mechanical GI obstruction.
Trulance Boxed Warnings
Boxed Warning
Risk of serious dehydration in pediatric patients.
Trulance Warnings/Precautions
Warnings/Precautions
Avoid use in patients 6–<18yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.
Trulance Pharmacokinetics
See Literature
Trulance Interactions
Trulance Adverse Reactions
Adverse Reactions
Diarrhea (may be severe), sinusitis, URTI, abdominal distension/tenderness, flatulence, increased liver enzymes, nausea, nasopharyngitis, UTI, dizziness.
Trulance Clinical Trials
See Literature
Trulance Note
Not Applicable
Trulance Patient Counseling
See Literature
Trulance Generic Name & Formulations
Legal Class
Rx
General Description
Plecanatide 3mg; tabs.
Pharmacological Class
Guanylate cyclase-C agonist.
How Supplied
Tabs—30
Manufacturer
Generic Availability
NO
Trulance Indications
Indications
Chronic idiopathic constipation (CIC).
Trulance Dosage and Administration
Adult
Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.
Children
<6yrs: contraindicated. 6–<18yrs: avoid.
Trulance Contraindications
Contraindications
Children <6yrs old. Known or suspected mechanical GI obstruction.
Trulance Boxed Warnings
Boxed Warning
Risk of serious dehydration in pediatric patients.
Trulance Warnings/Precautions
Warnings/Precautions
Avoid use in patients 6–<18yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.
Trulance Pharmacokinetics
See Literature
Trulance Interactions
Trulance Adverse Reactions
Adverse Reactions
Diarrhea (may be severe), sinusitis, URTI, abdominal distension/tenderness, flatulence, increased liver enzymes, nausea, nasopharyngitis, UTI, dizziness.
Trulance Clinical Trials
See Literature
Trulance Note
Not Applicable
Trulance Patient Counseling
See Literature
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