Colorectal disorders:
Indications for TRULANCE:
Irritable bowel syndrome with constipation (IBS-C).
Adult Dosage:
Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.
Children Dosage:
<6yrs: contraindicated. 6–<18yrs: avoid.
TRULANCE Contraindications:
Children <6yrs old. Known or suspected mechanical GI obstruction.
Boxed Warning:
Risk of serious dehydration in pediatric patients.
TRULANCE Warnings/Precautions:
Avoid use in patients 6–<18yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.
TRULANCE Classification:
Guanylate cyclase-C agonist.
Adverse Reactions:
Diarrhea (may be severe), sinusitis, URTI, abdominal distension/tenderness, flatulence, increased liver enzymes, nausea, nasopharyngitis, UTI, dizziness.
Generic Drug Availability:
NO
How Supplied:
Tabs—30
Pricing for TRULANCE
Constipation and bowel cleansers:
Indications for TRULANCE:
Chronic idiopathic constipation (CIC).
Adult Dosage:
Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.
Children Dosage:
<6yrs: contraindicated. 6–<18yrs: avoid.
TRULANCE Contraindications:
Children <6yrs old. Known or suspected mechanical GI obstruction.
Boxed Warning:
Risk of serious dehydration in pediatric patients.
TRULANCE Warnings/Precautions:
Avoid use in patients 6–<18yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.
TRULANCE Classification:
Guanylate cyclase-C agonist.
Adverse Reactions:
Diarrhea (may be severe), sinusitis, URTI, abdominal distension/tenderness, flatulence, increased liver enzymes, nausea, nasopharyngitis, UTI, dizziness.
Generic Drug Availability:
NO
How Supplied:
Tabs—30
