Trospium Chloride Ext-rel

  • Overactive bladder/enuresis

Trospium Chloride Ext-rel Generic Name & Formulations

General Description

Trospium chloride 60mg; ext-rel caps.

Pharmacological Class

Muscarinic antagonist.

How Supplied

Contact supplier

Trospium Chloride Ext-rel Indications


Overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.

Trospium Chloride Ext-rel Dosage and Administration


Take on empty stomach. 60mg daily in the AM. Severe renal impairment (CrCl<30mL/min): not recommended.


Not established.

Trospium Chloride Ext-rel Contraindications


Gastric or urinary retention; uncontrolled narrow-angle glaucoma; and patients at risk for these conditions.

Trospium Chloride Ext-rel Boxed Warnings

Not Applicable

Trospium Chloride Ext-rel Warnings/Precautions


Bladder outflow obstruction. GI obstructive disorders. Ulcerative colitis. Narrow-angle glaucoma (monitor). Intestinal atony. Myasthenia gravis. Exposure to high environmental temperature. Renal insufficiency (CrCl 30–80mL/min). Moderate to severe hepatic dysfunction. Pregnancy (Cat.C). Nursing mothers.

Trospium Chloride Ext-rel Pharmacokinetics

See Literature

Trospium Chloride Ext-rel Interactions


Additive anticholinergic effects with other anticholinergics. Increased drowsiness with alcohol; avoid consumption within 2hrs of administration. May alter absorption of other drugs (decreased GI motility). May potentiate or be potentiated by drugs eliminated by active tubular secretion. May be antagonized by metformin.

Trospium Chloride Ext-rel Adverse Reactions

Adverse Reactions

Anticholinergic effects (dry mouth, constipation, dry eyes, urinary retention, blurred vision), CNS effects (monitor), dyspepsia, headache.

Trospium Chloride Ext-rel Clinical Trials

See Literature

Trospium Chloride Ext-rel Note


Formerly known under the brand name Sanctura, Sanctura XR.

Trospium Chloride Ext-rel Patient Counseling

See Literature