• Viral infections

Trogarzo Generic Name & Formulations

General Description

Ibalizumab-uiyk 200mg/1.33mL; soln for IV inj after dilution; preservative-free.

Pharmacological Class

CD4-directed post-attachment HIV-1 inhibitor.

How Supplied

Single-dose vials (2mL)—2


Generic Availability


Trogarzo Indications


In combination with other antiretroviral(s) for HIV-1 infection in heavily treatment-experienced adults with multidrug resistant HIV-1 infection failing their current antiretroviral regimen.

Trogarzo Dosage and Administration


Give as IV infusion over ≥30mins for 1st infusion. May give subsequent maintenance doses as an IV infusion over ≥15mins or as an IV push over a 30-second period if no infusion-associated adverse reactions have occurred. 2000mg as a single loading dose administered as a diluted IV infusion, followed by 800mg (maintenance dose) every 2 weeks administered either as a diluted IV infusion or undiluted IV push.


Not established.

Trogarzo Contraindications

Not Applicable

Trogarzo Boxed Warnings

Not Applicable

Trogarzo Warnings/Precautions


Discontinue immediately if hypersensitivity reactions (including infusion-related or anaphylactic reactions) occur; treat appropriately. Immune reconstitution inflammatory syndrome (in combination with other antiretrovirals). Embryo-fetal toxicity. Pregnancy: may affect immune responses in infants exposed in utero; monitor for reversible immunosuppression; do immune phenotyping and consult expert. Nursing mothers: not recommended.

Trogarzo Pharmacokinetics

See Literature

Trogarzo Interactions

Trogarzo Adverse Reactions

Adverse Reactions

Diarrhea, dizziness, nausea, rash; lab abnormalities.

Trogarzo Clinical Trials

See Literature

Trogarzo Note


To register pregnant patients to the Antiretroviral Pregnancy Registry, call (800) 258–4263.

Trogarzo Patient Counseling

See Literature