Viral infections:

Indications for TROGARZO:

In combination with other antiretroviral(s) for HIV-1 infection in heavily treatment-experienced adults with multidrug resistant HIV-1 infection failing their current antiretroviral regimen.

Adult Dosage:

Give as IV infusion over ≥30mins for 1st infusion; may reduce to ≥15mins for subsequent infusions if no infusion-associated adverse reactions have occurred. 2000mg as single loading dose followed by 800mg maintenance dose every 2 weeks. Observe patient for 1hr after completing the 1st infusion.

Children Dosage:

Not established.

TROGARZO Warnings/Precautions:

Discontinue immediately if hypersensitivity reactions (including infusion-related or anaphylactic reactions) occur; treat appropriately. Immune reconstitution inflammatory syndrome (in combination with other antiretrovirals). Pregnancy. Nursing mothers: not recommended.

TROGARZO Classification:

CD4-directed post-attachment HIV-1 inhibitor.

Adverse Reactions:

Diarrhea, dizziness, nausea, rash; lab abnormalities.

Note:

To register pregnant patients to the Antiretroviral Pregnancy Registry, call (800) 258–4263.

Drug Elimination:

Half-life: 2.7–64 hours.

Generic Drug Availability:

NO

How Supplied:

Single-dose vials (2mL)—2

Pricing for TROGARZO

2 vials of 200mg/1.33ml carton (Qty: 1)
Appx. price $1907
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