Triferic Avnu Generic Name & Formulations
Elemental iron (III) (as ferric pyrophosphate citrate) 1.5mg/mL; soln for IV infusion.
Ampules (5mL)—5, 40; (50mL)—4, 24; Single-dose ampules (4.5mL)—10, 40; Packets— 1, 100
Triferic Avnu Indications
Iron replacement to maintain hemoglobin in adults with hemodialysis-dependent chronic kidney disease (HDD-CKD).
Limitations of Use
Not for use in patients receiving peritoneal dialysis. Not studied in patients receiving home hemodialysis.
Triferic Avnu Dosage and Administration
Administer as a slow continuous IV infusion over 3–4hrs via pre- or post-dialyzer infusion line, or a separate connection to the venous blood line. Give 6.75mg (undiluted) at each dialysis procedure.
Triferic Avnu Contraindications
Triferic Avnu Boxed Warnings
Triferic Avnu Warnings/Precautions
Monitor for hypersensitivity reactions during and after hemodialysis until clinically stable. Have personnel and resuscitative equipment immediately available. Determine iron status on pre-dialysis blood samples. Pregnancy. Advise females of reproductive potential to use effective contraception during and for at least 2weeks after therapy completion. Nursing mothers.
Triferic Avnu Pharmacokinetics
Triferic Avnu Interactions
Triferic Avnu Adverse Reactions
Headache, peripheral edema, asthenia, AV fistula thrombosis, urinary tract infection, AV fistula site hemorrhage, pyrexia, fatigue, procedural hypotension, muscle spasms, pain in extremity, back pain, dyspnea.
Triferic Avnu Clinical Trials
Triferic Avnu Note
Triferic Avnu Patient Counseling