Transderm Scop

  • Nausea

Transderm Scop Generic Name & Formulations

General Description

Scopolamine 1.5mg (delivers approximately 1mg over 3 days); transdermal patch.

Pharmacological Class


How Supplied


Transderm Scop Indications


Prevention of motion sickness and post-op nausea/vomiting (PONV).

Transderm Scop Dosage and Administration


Apply to dry skin behind ear; do not cut patch. Motion sickness: 1 patch at least 4hrs before required effect; remove after 72hrs. Apply a new patch if therapy is required >3 days. PONV (for surgeries except cesarean): 1 patch evening before surgery. Remove 24hrs after surgery.


Not established.

Transderm Scop Contraindications


Acute closure glaucoma. Allergy to belladonna alkaloids.

Transderm Scop Boxed Warnings

Not Applicable

Transderm Scop Warnings/Precautions


Wash hands and skin after use; avoid eyes. Monitor IOP in those with glaucoma. Psychosis. Monitor for new or worsening psychiatric symptoms. GI or urinary tract obstruction. Seizures. MRI skin burns; remove prior to imaging. Renal or hepatic impairment. Elderly. Pregnancy (avoid if severe preeclampsia). Nursing mothers.

Transderm Scop Pharmacokinetics

See Literature

Transderm Scop Interactions


Alcohol, other CNS depressants potentiate CNS depression. Additive anticholinergic effects with other anticholinergics, antihistamines (eg, meclizine), tricyclic antidepressants; monitor. May affect absorption of other drugs. Interferes with gastric secretion test; discontinue 10 days prior to testing.

Transderm Scop Adverse Reactions

Adverse Reactions

Dry mouth, drowsiness, blurred vision, dilation of the pupils, visual impairment, dizziness, somnolence, agitation, confusion, mydriasis, pharyngitis; difficult urination (discontinue if occurs), withdrawal symptoms may occur if used for >3 days.

Transderm Scop Clinical Trials

See Literature

Transderm Scop Note

Not Applicable

Transderm Scop Patient Counseling

See Literature