Transderm Scop Generic Name & Formulations
Legal Class
Rx
General Description
Scopolamine 1.5mg (delivers approximately 1mg over 3 days); transdermal patch.
Pharmacological Class
Anticholinergic.
How Supplied
Patches—4
Manufacturer
Transderm Scop Indications
Indications
Prevention of motion sickness and post-op nausea/vomiting (PONV).
Transderm Scop Dosage and Administration
Adult
Apply to dry skin behind ear; do not cut patch. Motion sickness: 1 patch at least 4hrs before required effect; remove after 72hrs. Apply a new patch if therapy is required >3 days. PONV (for surgeries except cesarean): 1 patch evening before surgery. Remove 24hrs after surgery.
Children
Not established.
Transderm Scop Contraindications
Contraindications
Acute closure glaucoma. Allergy to belladonna alkaloids.
Transderm Scop Boxed Warnings
Not Applicable
Transderm Scop Warnings/Precautions
Warnings/Precautions
Wash hands and skin after use; avoid eyes. Monitor IOP in those with glaucoma. Psychosis. Monitor for new or worsening psychiatric symptoms. GI or urinary tract obstruction. Seizures. MRI skin burns; remove prior to imaging. Renal or hepatic impairment. Elderly. Pregnancy (avoid if severe preeclampsia). Nursing mothers.
Transderm Scop Pharmacokinetics
See Literature
Transderm Scop Interactions
Interactions
Alcohol, other CNS depressants potentiate CNS depression. Additive anticholinergic effects with other anticholinergics, antihistamines (eg, meclizine), tricyclic antidepressants; monitor. May affect absorption of other drugs. Interferes with gastric secretion test; discontinue 10 days prior to testing.
Transderm Scop Adverse Reactions
Adverse Reactions
Dry mouth, drowsiness, blurred vision, dilation of the pupils, visual impairment, dizziness, somnolence, agitation, confusion, mydriasis, pharyngitis; difficult urination (discontinue if occurs), withdrawal symptoms may occur if used for >3 days.
Transderm Scop Clinical Trials
See Literature
Transderm Scop Note
Not Applicable
Transderm Scop Patient Counseling
See Literature