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Tpoxx Generic Name & Formulations
Legal Class
Rx
General Description
Tecovirimat 200mg; caps.
Pharmacological Class
Antiviral.
How Supplied
Caps—42
Manufacturer
Generic Availability
NO
Tpoxx Indications
Indications
Human smallpox disease caused by variola virus in patients weighing ≥13kg.
Limitations of Use
Efficacy in humans has not been determined. Efficacy may be reduced in immunocompromised patients.
Tpoxx Dosage and Administration
Adults and Children
Take within 30mins after a moderate or high fat meal. If difficulty swallowing, may open capsule and mix contents in 30mL of liquid or soft food (eg, milk, apple sauce, yogurt); consume entire mixture. 13–<25kg: 200mg twice daily; 25–<40kg: 400mg twice daily; ≥40kg: 600mg twice daily. All: treat for 14 days.
Tpoxx Contraindications
Not Applicable
Tpoxx Boxed Warnings
Not Applicable
Tpoxx Warnings/Precautions
Warnings/Precautions
Pregnancy. Nursing mothers.
Tpoxx Pharmacokinetics
See Literature
Tpoxx Interactions
Interactions
May potentiate repaglinide; monitor for hypoglycemia. May antagonize midazolam; monitor efficacy.
Tpoxx Adverse Reactions
Adverse Reactions
Headache, nausea, abdominal pain, vomiting.
Tpoxx Clinical Trials
See Literature
Tpoxx Note
Not Applicable
Tpoxx Patient Counseling
See Literature
