• Ocular infections

Tobrex Generic Name & Formulations

General Description

Tobramycin 0.3%; oph. soln; contains benzalkonium chloride.

Pharmacological Class


See Also

How Supplied

Soln—5mL; Oint—3.5g

Generic Availability

Soln (YES); Oint (NO)

Tobrex Indications


Susceptible infections of conjunctiva and cornea.

Tobrex Dosage and Administration

Adults and Children

<2mos: not established. ≥2mos: Mild to moderate infections: 1–2 drops every 4hrs or ½ inch of ointment 2–3 times daily. Severe infections: 2 drops every hr or ½ inch of ointment every 3–4hrs until improvement; then reduce before discontinuing.

Tobrex Contraindications

Not Applicable

Tobrex Boxed Warnings

Not Applicable

Tobrex Warnings/Precautions


Discontinue if superinfection or hypersensitivity occurs. Remove contact lenses before using. Pregnancy. Nursing mothers: not recommended.

Tobrex Pharmacokinetics

See Literature

Tobrex Interactions


Concomitant systemic aminoglycosides: monitor levels.

Tobrex Adverse Reactions

Adverse Reactions

Localized ocular toxicity, lid itching/swelling, conjunctival erythema, hypersensitivity; oint: may retard corneal healing.

Tobrex Clinical Trials

See Literature

Tobrex Note

Not Applicable

Tobrex Patient Counseling

See Literature