Tobradex St Generic Name & Formulations
Tobradex ST: is supplied as a 2.5mL or 5mL suspension in a 4mL or 8mL natural polyethylene DROPTAINER® bottle with a natural polyethylene dispenser tip and a pink polypropylene overcap.
Tobradex ST: Store at 2°C to 25°C (36°F to 77°F). Protect from light. After opening, Tobradex® ST can be used until the expiration date on the bottle.
Tobradex St Indications
Ocular inflammation associated with infection or risk thereof.
Active against the following common bacterial eye pathogens:
Staphylococci, including S. aureus and S. epidermidis (coagulase-positive and coagulase-negative), including penicillin-resistant strains.
Streptococci, including some of the Group A-beta-hemolytic species, some nonhemolytic species, and some Streptococcus pneumoniae.
Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species.
Tobradex St Dosage and Administration
Prior to Treatment Evaluations
Evaluate IOP prior to the initial prescription and renewal of the medication order.
Perform ophthalmic examination with the aid of magnification, such as slit lamp biomicroscopy, and, where appropriate, fluorescein staining, prior to the initial prescription and renewal of the medication order. Reevaluate the patient if signs and symptoms fail to improve after 2 days.
Adults and Children
Tobradex St Contraindications
Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and many other viral diseases of the cornea and conjunctiva. Mycobacterial infection of the eye. Fungal diseases of ocular structures.
Tobradex St Boxed Warnings
Tobradex St Warnings/Precautions
Intraocular Pressure Increase
Prolonged use may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision. Monitor IOP if this product is used for more than 10 days.
Sensitivity to topically applied aminoglycosides may occur.
May result in posterior subcapsular cataract formation.
May delay healing and increase the incidence of bleb formation when steroids are used after cataract surgery.
The initial prescription and renewal of the medication order should be made by a physician only after examination of the patient with the aid of magnification, such as slit lamp biomicroscopy and, where appropriate, fluorescein staining.
Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections. May mask infection or enhance existing infection in acute purulent conditions of the eye.
Re-evaluate patients if signs and symptoms fail to improve after 2 days.
Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex). Must use great caution in the treatment of patients with a history of herpes simplex.
Consider fungal infections in any persistent corneal ulceration where a steroid has been used or is in use. Fungal culture should be taken when appropriate.
Risk of Contamination
Do not touch the dropper tip of the bottle to any surface.
Contact Lens Wear
Do not wear contact lenses during the course of therapy.
No adequate and well-controlled studies in pregnant women. Increased risk of intra-uterine growth retardation with prolonged or repeated use during pregnancy.
Use during pregnancy only if potential benefit justifies the potential risk to the fetus.
Monitor infants born to mothers who received substantial doses of corticosteroids during pregnancy for signs of hypoadrenalism.
Nursing Mother Considerations
Use caution when administered to a nursing woman.
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk.
Safety and effectiveness in pediatric patients below the age of 2 years have not been established.
No overall differences in safety or effectiveness have been observed between elderly and younger patients.
Tobradex St Pharmacokinetics
Tobradex St Interactions
Tobradex St Adverse Reactions
Tobradex St Clinical Trials
Tobradex St Note
Tobradex St Patient Counseling
Storage and Handling
Store bottle upright and away from light. Shake well before use.
Do not touch dropper tip to any surface, as this may contaminate the contents.
Contact Lens Wear
Do not wear contact lenses while using this product.
Ability to Drive and Use Machines
May temporarily blur following dose administration. Use caution when operating machinery or driving a motor vehicle.