Ticlopidine Hcl

  • Thromboembolic disorders

Ticlopidine Hcl Generic Name & Formulations

General Description

Ticlopidine HCl 250mg; tabs.

Pharmacological Class

Platelet aggregation inhibitor.

How Supplied

Contact supplier.

Ticlopidine Hcl Indications


To reduce the risk of thrombotic stroke in selected patients intolerant of aspirin.

Ticlopidine Hcl Dosage and Administration


250mg twice daily with food.


Not recommended.

Ticlopidine Hcl Contraindications


Hematopoietic disorders including neutropenia, thrombocytopenia, or history of thrombotic thrombocytopenic purpura (TTP). Hemostatic or active bleeding disorders. Severe hepatic impairment.

Ticlopidine Hcl Boxed Warnings

Not Applicable

Ticlopidine Hcl Warnings/Precautions


Monitor for hematologic toxicity at baseline, every 2 weeks for the first 3 months, and for 2 weeks after discontinuation; test more frequently if signs of hematological changes occur. Discontinue if neutropenia or TTP occur. Renal or hepatic impairment. Bleeding risk (eg, ulcers). Discontinue 10–14 days before surgery. Hyperlipidemia. Pregnancy (Cat.B). Nursing mothers: not recommended.

Ticlopidine Hcl Pharmacokinetics

See Literature

Ticlopidine Hcl Interactions


Discontinue anticoagulants, fibrinolytics before use. Avoid aspirin. Potentiates aspirin, NSAIDs, anticoagulants, antipyrine, theophylline. Antacids reduce absorption. May be potentiated by cimetidine. Monitor phenytoin. May antagonize digoxin. Caution with propranolol, drugs that increase risk of bleeding, and drugs metabolized by CYP450.

Ticlopidine Hcl Adverse Reactions

Adverse Reactions

Diarrhea, GI upset, rash, neutropenia, pruritus, dizziness, anorexia, abnormal liver function tests, bleeding complications, hyperlipidemia, TTP, aplastic anemia, agranulocytosis, other blood dyscrasis, jaundice.

Ticlopidine Hcl Clinical Trials

See Literature

Ticlopidine Hcl Note


Formerly known under the brand name Ticlid.

Ticlopidine Hcl Patient Counseling

See Literature